Scott Resnick MD: Think Differently: What Drives Autoimmunity? Scott Resnick MD: Think Differently: What Drives Autoimmunity?
Episode 51

Scott Resnick MD:

Think Differently: What Drives Autoimmunity?

In this episode we are talking about the body's barriers, and how disruption of those barriers drives autoimmunity.  There are things we can do to support and protect our barriers and keep our "castle" safe, and Dr. Scott Resnick joins us to give us the know how.

First Aired on: Sep 5, 2022
Scott Resnick MD: Think Differently: What Drives Autoimmunity? Scott Resnick MD: Think Differently: What Drives Autoimmunity?
Episode 51

Scott Resnick MD:

Think Differently: What Drives Autoimmunity?

In this episode we are talking about the body's barriers, and how disruption of those barriers drives autoimmunity.  There are things we can do to support and protect our barriers and keep our "castle" safe, and Dr. Scott Resnick joins us to give us the know how.

First Aired on: Sep 5, 2022

In this episode:

In today's episode, Scott shares how disruption of our barriers drives autoimmunity, and steps we can take to start to return to health.  From maintaining our barriers, to reducing our exposures...we dive in to how to interrupt the chronic inflammation that may be driving symptoms.

Scott is a physician trained in General Surgery and OB/GYN and realized the need for a more integrative approach, bridging the gap between allopathic and functional medicine when he was practicing obstetrics in New Mexico.
Years after his training in allopathic medicine, Scott looked up the definition of allopathy and realized that the focus was symptom treatment.  He wanted to do more than that, and studied and began practicing functional medicine in 2012.

Living in a microbial/invisible world...we have selective, semipermeable barriers.  How can we support their optimization and keep them from creating a frenzied response that turns into autoimmunity?

King or Queen of the Castle
Let's think of ourselves as the King or Queen of a Castle.
When you build your castle, it will likely have gates, walls, maybe a moat, a drawbridge, friendly villagers waiting to defend you, perhaps and army at the ready.

Our body has protective/selective barriers as well!
Skin
Gut
Lungs
Blood-Brain Barrier
Blood vessels

We can take steps to reduce exposures and also allow our barriers to be selective when they defend us.
These systems operate on pattern recognition.

* Know what you are putting on your skin.  Are you slathering yourself in toxins?
Maintaining hormone balance (insulin/thyroid/cortisol) will keep your skin supple and protective.

*The gut - where up to 75% of the immune cells are in the lining needs to be able to take in nutrients AND fight intruders
Create a ceremony around eating:  think, prepare, smell look at your food...sit down, relax and enjoy your meals.
Chew your food really well.
Our digestive system needs time to break down our food and our enzymes break food proteins (which can be considered dangerous strangers by the immune system) into smaller, safer particles so that the alarms don't sound and the armies don't attack.
BREATHE!
Keep your cortisol and stress response in check in order to support the integrity of your barriers!


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Episode Transcript

[00:00:00] Julie Michelson: Welcome back to the inspired living with autoimmunity podcast. I'm your host, Julie Michaelson. And today we're joined by Dr. Scott Resnik and we're talking about how the disruption of our barriers can lead to autoimmunity and chronic illness and what we can do to protect them. Scott offers us his insight through relatable story and gives us actionable advice on steps.

[00:00:55] We can start taking immediately to help support our immune systems [00:01:00] and our overall health.

[00:01:03] Scott welcome to the podcast.

[00:01:08] Scott Resnick: Thank you so much for inviting me here. I'm looking forward to speaking with you.

[00:01:12] Julie Michelson: I am so excited to, to bring your perspective and different ideas to listeners. I was telling you before we hit record, I, I get really jazzed when it's something that I know, even if they've listened to every episode they haven't heard before. And so this is, this is one of those episodes for them. I'd love to begin with your story.

[00:01:38] I want listeners to get to know you a little bit and kind of find out, you know, why you're doing what you're doing. So whatever part of your journey you wanna share with us that led you to where you are today. Please share.

[00:01:52] Scott Resnick: Okay, I will do that and I'll try to keep it brief. So my name's Scott Reznick. I'm a physician. I was actually trained as a an OB GYN [00:02:00] and with these skills, I went to a town called Taos New Mexico which is one of the most unique places in the United States. And it's unique in the fact that still to this date, something like 20% of births are out of hospital.

[00:02:12] People have a different idea about, about health. They don't go racing to the doctors. And what I found is that even as a surgeon I was turning to more, what we would call alternative ways of looking at health to get my people better or might get my patients better. And so I found that instead of bringing people to surgery, I was working with their musculoskeletal system.

[00:02:30] I was working with their bowel function. I was working with their diet and so bit by bit, I, I, and also I've been using biodentical hormones in my. Female patients since 2001. So I guess I'm almost kind of like an old guard in terms of having, having used those. So what I started to realize is that there's a, there's a different perspective in terms of how we can be approaching health and in maybe 2010 or 2012, I did the fellowship with a four M so fellowship trained with AORM.

[00:02:57] I've put my surgical career on the, on the back [00:03:00] burner because my passion is you know, really helping to bridge this gap between Say a more conventional approach to medicine and what we refer to as function medicine. And I think there's a, I think there's a happy medium, you know, I don't wanna throw out the baby with the bath water that if I'm, if I'm stabbed I want antibiotics, generaled anesthesia and a surgeon.

[00:03:18] But I think that for, yeah, but I think that for so many of the chronic diseases that, that we're approaching it from the, from the, the wrong perspective. And what's interesting is that I trained as an apathic physician. I went to an apathic medical school, medical school did six years of postgraduate apathic residency training.

[00:03:35] And then when I'd been an apathic doctor for about a decade, I decided to look up apathy and see what it means. And I literally got on Google and I, I, I, I looked up apathy and I discovered that the apathic practice is the use of drugs, creams, potions, medicines, to counteract the symptom. So I spent four years in medical school, six years in postgraduate training, learning how to address symptoms, but at no point, did they ever get us to begin to [00:04:00] think about what could be driving these, these systems or what could be promoting these disease states?

[00:04:07] So I think that as a doctor or as a health coach, or as a nutritionist or anybody, when you, when you start to reframe your perspectives, We begin to get different answers. So it's, you know, if we keep on asking the same questions, we're gonna get the same answers. When we begin to look at different questions, we begin to get some different answers.

[00:04:23] Julie Michelson: Well I'm glad you didn't look that word up before you went to medical school or you might have chosen a different career path.

[00:04:30] Scott Resnick: that's possible,

[00:04:32] Julie Michelson: Yeah. And I'm laughing because I I'm, like, I wonder how many physicians have never looked up that word.

[00:04:39] Scott Resnick: right?

[00:04:41] Julie Michelson: so for me that question, the, the different perspective is the question why, right.

[00:04:48] Why. That's the question they don't really teach you to ask in medical school or, you know or, or discover, and you. Are all about thinking [00:05:00] different.

[00:05:00] Scott Resnick: right.

[00:05:01] Julie Michelson: and so I am really excited. And, and I'll let you start as broad as you want, but I want you to narrow down to this how the disruption, disruption of our barriers drives auto immunity, because this is a topic that's, it's so essential.

[00:05:20] And they're gonna hear about. The other parts of what I think you might touch on. But nobody's given us a deep dive in this idea of, of our barriers and why they're important and why they're compromised and what we can do.

[00:05:34] Scott Resnick: Right. Well, I think that as we discussed before this, before we got started here, I think that one of the most valuable ways that we can communicate complex ideas is through par. Right. I mean, the, you know, the shaman, the churches, they figured that out a long time ago that that people respond well.

[00:05:48] So I think to, to begin to introduce this idea, whatever I could do is, is to generate just a little story. All right. So imagine that, that we You know, we have our, our we're [00:06:00] humans, we're inside this body, right? And we need to protect the inner workings of our body. Now we live in, in an environment where we need to interact with our outside world.

[00:06:10] I mean, really any sentient living, being on this, on this planet needs to engage with the outside world. Primarily we need to eat. And we need to drink. Right. But it just so happens that there's this, this whole other life form that's out there, which is microbial and it's, it's invisible to us. So over the, the years that we've been on this planet, we've needed to develop a way to actually have selective.

[00:06:35] Permeable semi-permeable barriers that allow the things that we want to take in from the outside world, like food and nutrients and vitamins and water yet keeping out this microbial world that we are. Unable to see. So the parable that I'd like to develop is this idea of a king or a queen in his or her castle.

[00:06:55] Okay. So if you think about it you've got your valuable king or queen [00:07:00] and what they wanna do is they wanna protect themselves. So what they've done is they build a castle and that Castle's got strong fortified walls, right? If you're, if you go for the deluxe upscale castle, you've got a nice moat.

[00:07:12] That surrounds it. And because this is in the story, a benign king and queen, just imagine there, there are, there's a whole kingdom of peasants who love their king and queen and want to see that the king and queen are safe. So. What happens is, but yet, you know, of course there are, there are Moring people that want to come and take the, the king and Queens gold.

[00:07:34] So what they've done is they've set up and established. They've established a set of barriers that are that are hopeful to, you know, to keep them safe. So in some ways I see the human body as needing to establish barriers to the outside world. So we have a number of different barriers. You know, one of our barriers, our, our biggest organ in our body is our skin.

[00:07:52] Right. And as we know, that's a semipermeable membrane. We have our gut, which I'm sure you've talked about [00:08:00] Alesio at, at, you know, at mass general hospital and, and,

[00:08:04] Julie Michelson: somebody with celiac. He, he is

[00:08:06] Scott Resnick: oh my

[00:08:07] Julie Michelson: on my reading list.

[00:08:08] Scott Resnick: Oh, he's, he's, he's one of my favorite lecturers and, and thinkers, but, you know, he describes the fact that if you were to spread out this barrier of our gut, it's as big as it doubles tennis court.

[00:08:18] Now, if you think of the fact that our immune system is charged with protecting that barrier, it means we need to be able to find something which is 10 billionths of a centimeter. Virus in something which is as big as a doubles tennis course. So you can see that that task is Herculean. We also have barriers that, that are an interface with our lungs as well.

[00:08:39] So we need to be able to take in oxygen and expel carbon di oxide, but there are any number of different particles or viruses. I mean, look, we just went through COVID, you know, these are, these are, these are airborne. So. And then what's interesting is that when you can, so these are the main barriers that I think that our body is tasked to protect, but then if we go even farther and even even deeper into our [00:09:00] physiology, you can begin to think about other barriers such as the blood brain barrier.

[00:09:04] And there's also something known as the sub endothelial. Barrier. And what that is is that's the lining underneath our blood vessels. So when one really understands what's happening with cardiovascular disease you could actually make a really good argument that cardiovascular disease is an autoimmune process.

[00:09:21] The autoimmune

[00:09:22] Julie Michelson: like a functional medicine doctor?

[00:09:25] Scott Resnick: Oh no, the words out.

[00:09:28] Julie Michelson: I love it.

[00:09:29] Scott Resnick: So, so you

[00:09:30] Julie Michelson: You mean it's not just, just all cholesterol. It's not

[00:09:33] Scott Resnick: it's, it's not so cholesterol and the treatment is not the statin

[00:09:36] Julie Michelson: Yeah.

[00:09:37] Scott Resnick: So, so, so it's interesting. So what's, if I can just get into a little more of the science and again, I promise that'd keep this, this the simple, so,

[00:09:44] Julie Michelson: Keep it simple.

[00:09:46] Scott Resnick: At these, at these barriers are things known as antigen presenting cells and basically an antigen is anything that would stimulate our immune system to being revved up.

[00:09:57] Okay. So if you've, if you've got [00:10:00] celiac disease, the antigen you're most concerned about is is gluten, right? So what's interesting is that when you look at our physiology, so in an, an antigen presenting cell, basically, Identify as something in the outside world, you know, and what it does is it sends messages to our, the rest of our immune system.

[00:10:17] So it presents these antigens to the rest of the, of the immune system. So what's interesting is we've got antigen presenting cells in our gut. They're called dendritic cells. We have antigen presenting cells under our skin that are called longer Hans cells. So anything that penetrates our skin, maybe it's a mosquito bite.

[00:10:35] Maybe it's a, a brush with poison Ivy that can stimulate our immune system. And what's interesting is that last year there was a lab at Harvard medical school that actually showed that under the lining of our blood vessels are. You guessed it antigen presenting cells. So our whole immune system's job is to protect us across these barriers to to basically keep us safe because the truth, the matter is if you peel back my skin [00:11:00] and got a little scoop of Scott and set it on the, on the sidewalk, it would be teaming with bacteria, parasites, yeast probably within a matter of hours.

[00:11:09] So we need to maintain these barriers to be able to protect us from the outside world. And that's really what the entire immune system is charged with. It's keeping us safe. 

[00:11:18] Julie Michelson: Wow. And I knew, see, I knew you were gonna bring a different perspective. And I love, I, I love that idea. I'm like, all right, I want a moat. I want a Drawbridge. I want.

[00:11:29] Scott Resnick: Okay, so let's so let's, let's go back. Let's go back to that metaphor. So this is, this is not a misplaced metaphor. I haven't forgotten about it. So, so, you know, probably the easiest barrier to talk about is the gut. And I know that on your, on your show, you've had, you know, a number of people, a number of discussions about the gut.

[00:11:44] So I know that your listeners are probably pretty, pretty savvy about it. What's interesting is.

[00:11:48] Julie Michelson: to finally accept that, that the gut is, you know, a key player in auto immunity.

[00:11:55] Scott Resnick: Right. So I think it's probably one of the primary players. [00:12:00] And if you think about it over the course of the year, we all eat more, less 2000 pounds of food. So you can see that there's, there are a lot of molecules that are, that are making it into our body that need to be reconciled by our immune system.

[00:12:14] And an important thing that I wanna mention about the immune system is the immune system's job is it's it's pattern recognition. I mean, it's looking for molecules that have a shape, an electrical charge, a characteristic that just tells it that this is, this is a dangerous stranger, right? So what we wanna do is we wanna.

[00:12:33] Keep one, one maintain our barriers. And I'm gonna talk about how we can do that. The other thing we wanna do is, is make sure, do our very best to ensure that that the, our immune system is not being exposed to an antigen, a bacterium, a yeast, a food that could be setting it off into a hyper excited state, because ultimately I think that one of the most important things about what drives our immune system is this concept of molecular mimicry.

[00:12:59] Have you come [00:13:00] across that?

[00:13:01] Julie Michelson: I haven't, that's what I was thinking about when you were talking about this pattern recognition. I was like, ah,

[00:13:08] Scott Resnick: Right. Well, so

[00:13:10] Julie Michelson: because yeah.

[00:13:13] Scott Resnick: So the easiest way to understand that is to, I mean, many of us have kids, right. And when the kid gets strep throat what do we do ring up to the doctor? The doctor gives the kids some penicillin. Now here's an example where alopathic medicine might be realistic because what happens is that the, the, the strep bacteria actually has patterns and markers on it that resemble the vowels of our.

[00:13:34] So rheumatic heart disease is when you get a strap, you know, you're, you're infected by a bacteria again, probably going through our nasal sinuses and, and, you know, going across that barrier into our, into our body. But what happens is that dub immune system confuses those antigens with molecules that are actually normally present in our body.

[00:13:54] So I think one of the most. Important things to recognize is that to keep an immune system happy, [00:14:00] we want to one maintain our barriers and two keep to the best of our ability, everything that's that's in the realm of our immune system of these, you know, these dendritic cells, these cells that are constantly sensing and determining, you know, is our, is our environment safe?

[00:14:16] Our is our gut filled with bacteria that are helpful bacteria that are gonna downregulate our immune system. or is our gut filled with the bacteria that, that might keep our immune system RevD up. And then when we have too many of these patterns or molecules that that could potentially confuse our immune system, I believe that this molecular mimicry is, is a, a big part.

[00:14:36] And I know you've gone over some of this stuff. I mean, there there's a lot of studies looking at things like clubs, yellow and ansing spondylitis or rheumatoid arthritis. You know, there are a number of bacteria that are associated with rheumatological. Diseases. So I think that one thing that we can do is, is, you know, ensure that the molecules that we are exposing to our immune system across these barriers are as.

[00:14:56] Easily recognized and as helpful as possible. [00:15:00] So, you know, you and I both know what we're talking about. I mean, if it's, you know, if we're consuming organic foods if, if our body is digesting these foods down into smaller groups of amino acids and not long chain of amino acids, which are proteins that could be recognized as something else.

[00:15:16] What, and if we have a microbiome, you know, a hundred trillion. Bacteria in our gut that are the good type of bacteria, these immune cells that are on the other side of the walls and kind of keeping, keeping charge of what's going on are, are are down regulated. They're not getting into a, kinda like a worked up place where they need to create an autoimmune process, which by definition is an inflammatory process.

[00:15:39] Our body really has one way of combating these things and that is through inflammation. And as you know, inflammation is one of the most you know, it's the, it's the tide that binds of not only autoimmunity, but all chronic diseases. So diabetes, hypertension, cardiovascular disease, Alzheimer's disease.

[00:15:55] All these things are based in inflammation. So the, the name of this game is to one, maintain our [00:16:00] barriers. Two expose ourselves to the least number of molecules that could get our immune system out of whack. And three maintain the nutritional state that we can we can have a healthy, healthy immune system that's working well.

[00:16:12] And in a good, a real simple example about nutrition is just like vitamin D. I mean, you know, the amount of data that's out there between, you know, vitamin D and multiple sclerosis. I mean so, you know, there are a number of different things that we can, we can do to help maintain some of these barriers.

[00:16:25] And I promise I'm gonna get back to our discussion about the castle. Cause I think that's a you know, pictures, pictures worth a thousand words and why your listeners may not remember what I'm talking about. Hopefully they'll, they'll remember the, the, the image of, of this castle. Do you have any questions at this point

[00:16:39] Julie Michelson: I have so many questions, but not three hours. No, I, I want to dive into, because. I mean, this is it. And this is the key, right? I, I always joke if somebody were to just turn on a snippet in the middle of the podcast, it kind of sounds gloom and doom sometimes, cuz you know, we're like [00:17:00] we're exposed to all these things and all of

[00:17:03] Scott Resnick: Oh, right, right.

[00:17:05] Julie Michelson: so that's not why you and I are here talking today and, and while we have to set the stage and I, I do love the, the castle.

[00:17:13] I, I. That will stick with listeners and I'm a visual learner. And so I, I love it. Let's start to talk about the, the, how, like, what, what can we do? I mean, you mentioned kind of the key As far as, you know, the nutrition and, and limiting what we're exposed to. And, but really I, for me, the biggest thing I wanna dive into is, well, okay, how do we, how do we maintain those barriers?

[00:17:42] How do we protect them? But we probably do have to start with, because people are already listening. Their barriers are probably already in trouble.

[00:17:51] Scott Resnick: Correct.

[00:17:52] Julie Michelson: so, you know, wherever you wanna start with the, with the

[00:17:56] Scott Resnick: Okay. So, so probably one of the easiest thing to start with [00:18:00] is the skin, right? As I mentioned, that's the, that's the LAR largest organ. It is a, it's a permeable membrane to fat. I mean, you know, we put our hormones on our, our skin and they, and they make it into our body. I think one of the most important things that your listeners can do is know what you're putting on your skin.

[00:18:15] And you know, that there's a, there's a website, which is by the environmental working group, it's E wg.org. And there's a tab on that. That's entitled skin deep.

[00:18:26] Julie Michelson: Mm-hmm

[00:18:26] Scott Resnick: so this is, this is gold. I mean, so what we wanna do is we wanna remember, I mentioned these cells called longer ha cells, these, these antigen presenting cells that live under our skin, just make sure that you're not presenting any of these cells with anything that could be perceived as a toxin.

[00:18:41] So they've got.

[00:18:42] Julie Michelson: if you are not already taking the steps to make sure you are actually putting tons of toxins all over your skin all the time.

[00:18:52] Scott Resnick: Right now, the other thing we can do is we can also ensure that, that we have I haven't talked about this, but there are three hormones that are involved in balancing our body's [00:19:00] energy, which is insulin, thyroid and cortisol. I think many of your listeners I'm sure have struggled with the state of hypothyroidism, if not Hashimotos and what is one of the classic signs of, of hypothyroidism its dry skin?

[00:19:15] So you can imagine that as our, our skin gets dry, it doesn't function as well as, as a barrier. If we have high cortisol from too much stress cortisol by definition, diverts blood away from our skin, because it's intent on keeping our brain and our heart alive. So if somebody has dysfunctional cortisol that can similarly affect the way that the, the skin is perfused, the amount of blood flow that we get to our skin.

[00:19:40] So the I'd figured I'd start with the barrier of the skin. It's our biggest organ. I think it's really important to, to ensure that you're not putting any kind of any kind of toxin. On your skin. The next biggest barrier is our gut. Okay. So if we go back to the castle metaphor, right? When you build your castle you don't wanna build it with a bunch of cracks in the [00:20:00] wall and, and, you know, a draw, a Drawbridge that doesn't, you know, that doesn't work well.

[00:20:04] So. Yeah, don't wanna leave it. Don't wanna leave it half open and it turns out if you're the king of the queen and you've got your guards who are guarding your castle, you don't want, 'em hanging out in the, in the basement, in the mess hall, you know, drinking, drinking gro and, and telling war stories. You want them up on the, on the margins, on the pyramids of your castle.

[00:20:22] So is it any wonder that 75%, maybe 60 to 75% of our immune cells in our body are located within one centimeter of the blinding of our gut? so it's almost as if this, the, the king of our, you know, of, of our castle, of our body's castle had said let's send out our, our guards to the, to, to the barriers. And while we're talking about the the gut if you were to, so let's say you went, you know, you sprung for the moat.

[00:20:50] When you, when you build your castle, would you prefer to fill that moat with water or acid? Well, I'd probably choose acid because that's [00:21:00] gonna, that's gonna actually help you. So, so now if we wanna surround our, our, our moat with acid, we can do the same thing in our gut. So it turns out that having a healthy stomach with the cells that make hydrochloric acid, if we're acidifying our gut. Then that's one of our first lines of defense against these, you know, these invisible microbes that, that are coming in on the 2000 pounds of food that we eat, eat every year. So if you take your car and you spin it into McDonald's, while you're on the phone and you've gobbled down a hamburger, you haven't taken the time to activate your, your you know, your brain to tell your, your gut to start making stomach acid.

[00:21:41] What happens? You gobble down to Hamburg. If it's not broken down well into small groups of amino acids, like 1, 2, 3, or four, but because you don't have the proper stomach acid to break down our proteins, you know, you've got these more complex protein chains. All of a sudden those can start to look like some of these molecules that are the [00:22:00] dangerous strangers that are the immune stimulating antigens.

[00:22:04] So.

[00:22:05] Julie Michelson: And I'm wanna, I'm going to be really naughty because we don't have enough time to cover everything I wanna cover anyway, but you brought up one of my biggest pet peeves in the alopathic medicine world. I wanna talk a little bit more about stomach acid because.

[00:22:23] Scott Resnick: Mm-hmm

[00:22:24] Julie Michelson: So many people by the time they find me are on proton pump inhibitors

[00:22:30] Scott Resnick: mm-hmm

[00:22:30] Julie Michelson: we're, you know, just ti they ha they're, they are not breaking down their food at all.

[00:22:36] And. Gosh, that could be just a whole nother episode. So I, I, I don't

[00:22:42] Scott Resnick: have to reschedule.

[00:22:43] Julie Michelson: I, I know I don't wanna get to, we just do one per system, but, but I, I would just kind of want you to reiterate a little bit why? Because people think one of the really common systems as people are in this chronically inflamed state is [00:23:00] heartburn.

[00:23:00] Scott Resnick: mm-hmm

[00:23:01] Julie Michelson: And then they're they, the one approach the, the Western typical Western approach is well let's squash that acid.

[00:23:12] Scott Resnick: right,

[00:23:13] Julie Michelson: Then we're losing motility. We're it's this, it's this battle. So I just kind of wanna highlight what, what you said, because I, I always address it with people in taking that functional approach of, well, no, you actually probably were getting heartburn because your acid was already suppressed and.

[00:23:34] It wasn't closing. And you know, these are the same people that are constipated because now they've really, their whole system has just slowed down. But you gave me like a whole new let's highlight again that like, we need that stomach acid

[00:23:51] Scott Resnick: Mm-hmm and I've got, you know, I'm, I'm a fan on, on discussions like this, or like, you know, cuz people are listening to this or thinking, what, what can I do about this? I go to my doctor, they're [00:24:00] putting me on the proton pump inhibitors. Here's a couple really simple things you can do starting tonight. To increase your production of your stomach acid.

[00:24:08] So there's something in our body, which is known as the Selo gastric. Reflex. Okay. SLO like cephalic head gastro, meaning stomach, right. And what this is is this, this is the preparatory stage that our body needs to begin to prepare itself for the digestive process. So what can you do to help that Cephalon gastric reflex while driving into the McDonald's while you're talking on your cell, phone't it?

[00:24:33] What you can do is you can begin to create a little bit of ceremony around eating. And so what happens is, as we think about food, as we prepare the food, we smell the onions that we're dicing. We, we, you know, we, we we smell the soup that, that that's getting ready. We, we you know, we prepare ourselves to eat.

[00:24:50] One of the simplest things that people can do is create this degree of ceremony around eating. And like I said, this is something that your listeners can start to do tonight. And what is that? It means don't [00:25:00] sit and eat in front of the TV. Set a place by, by the table you know, go out to the bed bath and beyond, and spend $12 on some napkins lights and candles you know, turn have people take their cell phones and, and turn them off because our body wasn't meant to digest food while we race from place to place under you know, fluorescent whites.

[00:25:17] No, we, we,

[00:25:18] Julie Michelson: anyway, cuz that's not where that's not where our energy is. I love, I love that because I see, I, I love just even the change in wording. People have heard me talk about, I heard other guests talk about mindful eating and, and this is what you're talking about, but I like this idea of ceremony around.

[00:25:38] We start to digest before we put food in our mouth. We start to get our digestion going and, and looking at your, like, taking a moment, like make your plate pretty,

[00:25:50] Scott Resnick: right,

[00:25:50] Julie Michelson: look at it before you even take your first bite. These are the things that are, are so important that may. Sound like luxuries. [00:26:00] But as, as you mentioned, like, this is how we are designed to, to digest our food.

[00:26:07] Scott Resnick: Exactly.

[00:26:08] Julie Michelson: see, I had no idea you were gonna go there. I love that.

[00:26:10] Scott Resnick: And, and so, so, so the next simple thing you can put this into place tonight is, and I know you've talked about this before is chew your food. right. I, I mean, really what, what we're trying to do is we are avoiding these complex proteins, these, these three dimensional shapes of, of amino acids and electrical charges and stuff that are going to be recognizable.

[00:26:30] Molecules by our immune system. So what we know is we know that if the immune, if the immune system, and again, remember three quarters of our immune system is lining our gut. If they're exposed to smaller segments of immuno acids, like one, two, Then height one, two or three, four one, two or three, four amino acids.

[00:26:49] Those are recognizable patterns. Those are, those are friend. Those are friendly. Like in other words, immune system says, great. We're we're getting fed. We need those amino acids to run our biochemical processes. But if you're [00:27:00] not taking time to eat, if you're not making a digestive stomach acid, you're not activating your digestive enzymes.

[00:27:06] You're sending poorly digested proteins down into our lower parts of our gut, where the immune system starts to, you know, get a crack at what's happening. You could conceivably, or you probably are sending these more complex collections of amino acids. And that's what a protein is. A protein is a, is a string of amino acids, much like, just imagine to remember those bar magnets we used to play with when you were kids.

[00:27:28] So if you, if you hang 'em end to end, they're just nice and straight. But if you kind of cl 'em up together, they form like. They kind of all stick together and form a ball. That's what happens with proteins in our body. And if you were to take a, you know, you know, that there's gonna be different magnetic forces, you know, different places in that, in that ball.

[00:27:44] So, so it's, it's it's structures that look just like that, that our immune system is recognizing. And ideally we have an intact barrier to our gut because what happens is that as those barriers begin to break we start [00:28:00] to increase the potential that some of these injurious dangerous strangers.

[00:28:04] If I could use a, you know, I like that term can, can now elicit response from our immune system. And like we talked about earlier, the immune system has. One way of combating these dangerous strangers, which is inflammation. And that's really at the core of of autoimmunity. And I know we're running out of time, but let me just say one other thing, which is if you go on with, with, with the metaphor of the castle, right?

[00:28:24] Because remember we've got a, we've got a kingdom that loves the king and queen, right. So switch that thinking over in your mind and think about those aren't peasants, but they're bacteria. They're the healthy type of bacteria that actually have been shown to down regulate our immune system. So what happens when a you know, a horseman wearing all black with a face shield and a big sphere starts wandering into the, into the, you know the, the township.

[00:28:47] Words can make it back to the, to the, to the kingdom that, that something's happening. So that's the same. That's how I'd like to look at our relationship with bacteria, because if we have the right type of bacteria, you know, they're sort of in this metaphor akin to, [00:29:00] you know, this, this peaceful cooperative kingdom, you can see how as though, as that starts to change, if the knew the opposing thera gals start, you know, coming in on horse, We're gonna, we're gonna be able to get some early warning as well.

[00:29:14] So with all those metaphors, you know, of having a, having a healthy mode, having intact barriers of our castle, having our immune system, which is situated like the guards at the parapets at the, at the Drawbridge, not leaving the Drawbridge down at night and having a, a kingdom of bacteria read you know, happy peasants in your kingdom who are willing to help to, to keep the peace that, that all that together works to maintain a healthy, balanced immune system.

[00:29:40] Julie Michelson: I, I just love that visual and I wanna highlight for people because we hear, and you did such a beautiful job. The happy peasants, you know, I've. Many times we tend to hear bacteria and think bad and like, no, not all bacteria, most, most isn't. And, and so I love that you, you [00:30:00] were able to, to paint that.

[00:30:02] Picture for us as well as the way the system is set up, as you mentioned is to protect us. It's when we've got these chronic alarms, you know, too many marauders that are, it's just one after another, that we get into this spiral. And, and that's what we. Can shift. I'm gonna ask you a question. You may not have known.

[00:30:28] I was gonna ask you which is probably dangerous as we're getting close to, to time, but is autoimmunity healable can we heal?

[00:30:38] Scott Resnick: I would say yes,

[00:30:40] Julie Michelson: Oh, well, thank goodness. I, I guess I was rolling the dice.

[00:30:43] Scott Resnick: I, I, I, I think it can, I think it can be healed. I think that it's, it needs to be looked at as sort of a, a chronic chronic disease with a, a potentially acute exacerbations. So I do think that we can, we can undertake a series of systematic. Steps to optimize the way [00:31:00] our, our nutritional balance to ensure that the way that our body handles energy, which is insulin, thyroid, and cortisol to make sure that's all, all, all in balance to ensure that our, our, our gut bind is intact, that we're not putting toxins on our uh, on our skin and finally to maintain that all of our detoxification pathways are up and running, which mandates having a working gut and a working skin.

[00:31:20] So you can seek and sweat, I I'm of the belief that, that you know, sort of like once auto immunity happens, I think the horse is sort of out of the proverbial barn. So to speak, but I do think there is a lot that we can do to, to sort of Mo that, to kind of keep it, it tamped down and, and it takes, you know, working with someone like yourself or someone like, like me who can actually have a coherent science based approach that, that allows us to look at this in a, in a way that's doable.

[00:31:48] So I do believe that that that autoimmunity can be managed if not fully cur.

[00:31:55] Julie Michelson: Yeah, I, I, I totally agree. And, and listeners now, you know how my [00:32:00] life is, I've done a 180 But I, it is. So I, I look at, in my life I'm symptom free, but I'm also always taking steps.

[00:32:11] Scott Resnick: mm-hmm

[00:32:11] Julie Michelson: To stay that way. One of the tricks and I, I didn't really it's not something I, I don't think I've ever shared on the podcast that's ever come up before.

[00:32:20] You know, one of the things I do, I don't eat out often. I like to be in control of my food and, and we love to cook and we love to eat clean. But when I'm traveling or I do eat out. I, I will take enzymes because while my gut is healed and in a great place, especially compared to where it was when I was actively sick.

[00:32:41] I look at that as insurance, right? It's like extra

[00:32:45] Scott Resnick: Right 

[00:32:45] Julie Michelson: because I don't know exactly, you know, I, I know what. Think is in the food. And it's like, oh, I'm not even gonna gamble. I'm just gonna, you know, grab myself some extra peasants

[00:32:56] Scott Resnick: Right. I, I, I love it. And, and, you know, here's another one of these, one of these [00:33:00] kind of funny things where, you know, there's this myopia of, of, of mainstream medicine, cuz how many people have gone in and said there are doctors, should I take some enzyme? The doctor goes, ah, that's no good. There's no reason for enzymes, but if you have a head of the pancreas cancer and you've got a Whipp procedure where you take out the pancreas, they give you.

[00:33:16] Enzymes, because we know that the enzymes can be taken orally and that they work to help digest the food. So I, I love the fact that, I mean, so these are all simple things that, that, that, that we can do. I think the ceremony of eating is important. I actually have an Instagram site which is @whatyourdociseating.

[00:33:34] shows what I eat, because I, I mean, another thing which I think is important is it's it's is being healthy, takes. And, and, and I know that that's something you, that you've talked about. It takes a little extra effort to go to the store. It takes some time to learn how to prepare your food. It takes some time to sit down and light the candles and fold the napkins and do the dishes and all that kind of stuff.

[00:33:53] But the payoff is a life of health. So what I do is I'm, I'm a doc. Who's not like do, as I say, but do, as I do, [00:34:00] I created an Instagram site that, that basically just shows how I eat. And so it's. What your doc is eating and I'm sure you'll look at it after this. You know, if you haven't

[00:34:10] Julie Michelson: I'm totally gonna check it out. I haven't that one I haven't seen. And I do wanna let listeners know. We. Links in the show notes. But you, it, somebody who wants to spend six weeks working with you on all of these foundational things, I know that you've, you've got your program up and running which is an amazing opportunity for people to not only learn from you, but learn in community which is so effective and, and.

[00:34:36] We'll have those, those links too. You already gave us. I always ask at the end of the podcast, what's one step listeners can take. You can reiterate if, if, if it's the ritual or it's your opportunity to sneak in another one, it's up to you.

[00:34:51] Scott Resnick: No, this is, this is something I know that you've spoken about on your podcast. And it's, it's, it's one of the simplest things that we can do, but it's probably one of the most important. And if I could [00:35:00] give you a one word answer, it would be breathe.

[00:35:02] Julie Michelson: I knew you were gonna say that

[00:35:04] Scott Resnick: And I know it's funny because there's, you know, that we could talk about, you know, like the dendritic cells and the different arms of the immune system and the different enzymes you can take.

[00:35:13] But at the end of the day, the most important thing that we can do to maintain a state of health is to keep our cortisol and our stress response in check because cortisol, diverts blood away from the, from the. It diverts blood away from the gut. And it would make sense that if, I mean, I didn't mention this, but you know, the lining of the gut regenerates itself every three days.

[00:35:34] So if it's not getting the right amount of blood flow, then you're increasing the risk that the, those cells that line, the interior of the gut, instead of being like nice, connected like this, they start to develop some leakiness

[00:35:48] Julie Michelson: I always talk about the brick wall behind me. That's

[00:35:51] Scott Resnick: that's right.

[00:35:52] Julie Michelson: that's my it's my gut barrier.

[00:35:54] Scott Resnick: See, see, see, you've been thinking about barriers for, you know, for a long time.

[00:35:57] We just needed

[00:35:58] Julie Michelson: I have.

[00:35:58] Scott Resnick: get on the show and

[00:35:59] Julie Michelson: [00:36:00] it's just exactly, it's all putting it in language. People understand. And again, for people who learn, like I do giving the visual people, listening on audio right now are like, what wall behind her, you know, they, they have no idea what I'm talking about. So what, what amazing. Gold.

[00:36:17] And I know you just gave listeners that what your doc is eating is where to find you on Instagram, which is fan. I can't wait to check out what you've been eating. And, and

[00:36:26] Scott Resnick: I have to warn you that I'm not, I'm not, I'm an omnivore. And I,

[00:36:29] Julie Michelson: as am I well, we wanna be healthy.

[00:36:33] Scott Resnick: I am a big fan of the, of the of the statement eat a rainbow. Right. 

[00:36:36] Julie Michelson: One of

[00:36:37] Scott Resnick: and, and, but I think the most.

[00:36:39] Julie Michelson: I say, I, you know, yes, I have a plant. Once people say they eat plant-based, I'm like, you have to define that for me, because I say I eat plant-based as well. But I also eat

[00:36:50] Scott Resnick: right.

[00:36:51] Julie Michelson: meat and wild caught fish and you know,

[00:36:53] Scott Resnick: I think, I think that's, that's what our body needs, because we start to look at it from a metabolic standpoint. There are essential amino [00:37:00] acids that our body can't make. There are essential fatty acids that we get in fish, like the omega3s and don't get me started talking about omega3 a index and autoimmunity, cuz that, that would probably require a whole additional podcast.

[00:37:12] Julie Michelson: I, we could do one on like DS, omega threes, you know, we, we could just make a little list of formal, you know, the whole, the whole thing. So Scott, thank you. Thank you. Thank you so much. You've shared amazing gold. You've done it in a way that hopefully was as fun for listeners as, as it was for me. I'm I will quote you every time, but I will.

[00:37:35] I am stealing your cast. Or I'm building my own. How about that?

[00:37:40] Scott Resnick: that's that's I hope, I hope, I hope that everybody out there builds a castle. And I just want you to say that it's really been my pleasure. I, you know, I still look for these opportunities to be able to share knowledge. I mean, I think we're, we're entering a new time and that time is characterized by.

[00:37:53] We were talking about this earlier democratization of medicine. I mean, let's, let's make a, a cogent science based [00:38:00] compassionate, realistic way of healing. That isn't reactive. That's not just alopathic. And I think so, given any opportunity to be on a podcast or speak to someone like yourself, I'm going to jump at it.

[00:38:12] And really this was, this has been as as enjoyable for me as it as it was for you. And I just wanna thank you for giving me this opportunity to, to, to share this and, and, and the, the castle is royalty free, so

[00:38:23] Julie Michelson: go. love it. I love it. It truly, truly my pleasure. And for everyone listening, remember, you can get the show notes and transcripts by visiting inspired living.show. I hope you had a great time and enjoyed this as much as I did. I will see you next week.
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Scott Resnick MD

I am a physician, formally trained in General Surgery and OB/GYN but focusing exclusively on functional medicine for the last decade. I completed a fellowship in Antiaging and regenerative medicne with A4M in 2012. More recently I have been focusing on medical technologies, teaching computers to think like physicians, and promoting a systems-based approach to medicine that empowers individuals to be the best stewards of their health care.

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