[00:00:00] Julie Michelson: Welcome back to the inspired living with auto-immunity podcast. I'm your host, Julie Michaelson. And today I'm joined by Kelly Lupsha, an expert on women's health and energy and longevity. Her ultimate purpose is to teach people to become the CEO of their own health, which is one of the reasons I am so excited for our conversation.
[00:00:56] Today, we're talking about gene activation and how we can [00:01:00] use our unique blueprint Nutrogenomix and lifestyle to quote, turn the power back on whether you're interested in reversing illness or preventing it. This is a must listen episode.
[00:01:12] Kelly welcome to the podcast.
[00:01:14] Kellie Lupsha: Hello. Thank you so much for having me on Julie. It's a pleasure.
[00:01:18] Julie Michelson: I am so excited to dig into all the things that I know we want to talk about today. But I always love to start out with. A little bit of your story, you know, how did you come to be interested in this very specific fields that you're practicing in? You know, how did you get here? I know, I know the field is new enough and, and wasn't even a, really a thing when we were kids.
[00:01:46] So tell us how you got here.
[00:01:49] Kellie Lupsha: Yeah. So thank you. You know, I, I started my journey truly in traditional. Medicine as a physical therapist and I've always loved what I've done. And I have felt [00:02:00] very blessed that I've had the gifts to help people that have gone through some very significant trauma in their life. From massive strokes, traumatic brain injuries, concussions, a variety of neurological disorders.
[00:02:11] And then it was probably just about the same time that my father, about 14 years ago passed away of cancer at the age of 69. And there was no cancer in his family. And I started to question and wonder, how did he get this? What happened? And he then didn't have an opportunity to really get to know and spend time with his grandchildren.
[00:02:33] And I thought, well, what about my life? I want to be sure I'm there for my grandchildren. So, what did he do in his life that potentially created this cancer that maybe I could avoid? And so it was really eyeopening for me. One obviously very sad to lose my dad early, but at the same time in my practice, my husband and I, who we share our practice together, we started saying. [00:03:00] more can we give our patients? What more can we do for our patients beyond just our, you know, our unique approach and physical therapy of what we were doing. And that's truly, when we found functional medicine, we started realizing, wow, if we can help get to root cause with patients, if we can help them improve at a cellular level, their poor bodies were full of inflammation and so much more.
[00:03:22] And then it was a very interesting time because when we were going back to doctors who had referred clients still in the traditional medicine world, they had no idea what we were asking. Right. Because. People weren't really looking outside the box of traditional medicine yet. And when you have a serious medical injury or illness and you land in the ER, right, you need every piece of modern medicine that we have.
[00:03:47] Julie Michelson: Absolutely.
[00:03:48] Kellie Lupsha: And but then after that, the journey of healing is, is vast. And I think several, so several of us all along the way have ended up having something happen to us in wonderful. [00:04:00] This is w odd symptom. This is an odd this, and throughout the course of my four children, we'd have things. And all of a sudden, kind of an, all this time, I was like, oh my God.
[00:04:11] Our genes are not our destiny. Oh my gosh. We are in more control of our life than ever through lifestyle diet. More. I can really flip the switch on or off of genes. That's how this is working. And so one learning about this that people can really create that unique blueprint for them and that too, we can use, you know, not only lifestyle, but Nutrogenomix and plant-based medicine to help the body heal and repair.
[00:04:38] And when we started integrating this. Both with my clients in the clinic and people online, it was just a game changer because people weren't didn't feel that they were slaves to their genes, but at the same time started feeling better, pretty quickly. And didn't think they could before. And, and it's just been amazing.[00:05:00]
[00:05:00] Julie Michelson: I love that I, we were chatting before we hit record. And so, you know, I. I'm all about people being empowered and realizing, you know, it's it's, you are not your diagnosis, your diagnosis, isn't your destiny. And even more importantly, your genes, aren't your destiny. And we say in functional medicine all the time, genetics may load the gun, but environment pulls the trigger.
[00:05:25] And for many of us, myself included genetics. Didn't love the gun. So I'm nobody in my family with auto-immune before. At least that we knew of and my labs, but, you know, I have no genetic tendencies for rheumatoid arthritis. And so I love. What you're doing because people, the more people that know, you know and I love how it's like, okay, not it's your it on the one hand you're like with treatment, we can treat better.
[00:05:58] But at the other end, it's like, oh, well, we could just [00:06:00] prevent, like, let's just not go.
[00:06:01] Kellie Lupsha: Right. Yeah.
[00:06:02] Julie Michelson: Not go there. And I like you. I, my dad was 54 when he passed and didn't know his grandchildren. And I have so many questions. I know his passing was extremely sudden and unexpected and so, and it's like an. Y. And how do I not do that?
[00:06:21] Then now I had thought that was going to be my destiny as well. That's how I, why I got into functional medicine also. So we share that in common.
[00:06:31] Kellie Lupsha: Yeah, it's really fascinating. My maternal grandmother had breast cancer. So in my young adult life, I just was like with the, with the one in seven women and my mother didn't have it. And so I basically thought I was destined to happen. And what is really interesting is I do not have those genes, which is great.
[00:06:50] However, what I've learned is even if you have the genes, but they're very, very say low penetrants, right? Not top of the list for you of your concern. [00:07:00] If you don't address other things and you let your inflammation go rampant that turn on all these other genes. So like, you're like, I am a rheumatoid arthritis wasn't in my family, but whatever was going on for you decided to light that Gina.
[00:07:19] Julie Michelson: Yeah, yeah, absolutely. It's, it is amazing. So I love, you know, again, Treatment approaches, but PR preventative medicine. I mean, you know, anti-aging all of it optimizing. I just had a conversation with somebody who I didn't know, was talking to me because she was interested in what I do as a, as a client.
[00:07:42] I had no idea that wasn't how we were interacting. And and so she was asking, she has never auto immune and she was asking about what I do and you know, what, what would, what would that, what does that look like for someone who would, and it's unlike it's, it's the same. So wherever you are right at your Optima [00:08:00] and I started, and the fun thing is I started asking her questions about her energy level and how she feels when she gets up in the morning and this and that and the, you know, and the whole, like, no, I feel fine.
[00:08:13] She literally said like, oh, I could just fall asleep, you know, in my car at any moment. Like, that's how fatigued she is, but she's been told she's a mom and whatever, you know? And so I'm like, oh, you could feel,
[00:08:29] Kellie Lupsha: Well, and, and really like speaking to women from, you know, like say 45 to 65 or something somehow along the way, it just. Oh, yeah, we're just aging expect you're running around ragged. You're always doing too much. You don't care for yourself. You're just getting older. Oh, it must be hormones. Oh, like there's this such this excuse for common.
[00:08:50] And when I tell people, if you're talking common, none of us want to be common. Right? You should be doing something different to get you out of that though. That's [00:09:00] not common, but when enough people talk about it, then it just must be normal. Right? I said it, maybe it's common, but it's not normal. So that's such a great
[00:09:09] Julie Michelson: is never an area you want to be average. Like you want to be outside that bell curve. I say, I know you use labs a lot. We use extensive lab testing and people get concerned, you know, like, oh my gosh, my omega threes got flagged because they're too high, you know, should I be worried?
[00:09:29] You know, I'm like, okay. Labs are done on a bell curve, you know, there no look at our country. Like, do you want to be the average of all of the unwell people? No, you do not want to be average. So I I love so many things that you are doing and have done are areas of interest for me. So I. I am going to ask you to reel me in if I need to.
[00:09:55] I want, I want to really give listeners just [00:10:00] usable information, but I think so much of this conversation is possibly new for them. So I wanna, I want to even just start. Really at the beginning. Cause you mentioned already what we're going to be talking about. And so we're going to start with, what is Gina?
[00:10:20] What do you mean? You said turn genes on and off gene activation and we just touched on it. You just gave examples, but really explain to listeners what that is.
[00:10:31] Kellie Lupsha: Yeah. So, you know, for, for most of our lifetime, and what we've heard in that in the past is, you know, whatever your genes are, that's in your family. So if you haven't, if genes for heart disease, diabetes, cancer, then you'll have them. Okay. So when you look at doing a DNA study to really map out what your genes are, that's just your bloopers.
[00:10:57] And if you think about it as a [00:11:00] piano, right? The piano has the same. We have all, basically we're all very, very alike, much, much. We're barely all different in our genes. And so when you look at that, you could take 10 different people to play that piano. And it's going to sound differently, right? Somebody who is a beautiful concert pianist to somebody who's never even played the piano before.
[00:11:21] And so if you think about that in your genes, our genes are just the. But how they show up. Meaning when we say expressed is, is that gene turned on and we have good genes and bad genes. So of course all the protective genes, all the good genes, genes that control our own body's ability to fight inflammation, genes that produce our own bodies and eye oxidants.
[00:11:46] Those are like the, the good things, right? Like your vitamin C, your blueberries, your kids. Our own body's ability to detoxify or get rid of toxins chemicals, the bad things in our body. So we want those sorts of [00:12:00] genes to be active and working. And so our body feels great. And naturally, if our body's Intune and the genes are working optimally, we feel.
[00:12:10] We also have genes that could lead to health, disease issues, right. Genes that could lead us down to, you know, obesity and diabetes and cardiovascular disease cholesterol. So those genes. Yes auto-immune. Absolutely. And so those genes typically don't start off with. Expressing, we may have them. And in each one of us knowing our DNA, some of them, like I was saying earlier could be a low penetrance.
[00:12:38] Like you probably won't get it. And the less something else really triggers you. Right. Or it could be very, very high penetrance for you, meaning you are very, very high risk for getting this. And so when we talk about gene activation literally it could be a light switch on or off, meaning you want the gene to protect yourself.
[00:12:57] Or you want to turn off the gene, flip it off that [00:13:00] switch that are harmful to us. And, and we look at your roadmap. So let's just say a client comes in, has their DNA tests done. It actually doesn't matter what it says, knowing what it is. You can develop a roadmap around it. So let's just give you a quick example, Julie.
[00:13:20] If you were going from Colorado to California and we knew, Hey, come to visit. And we knew that without any traffic and we Google map it, it's going to take you right. Just say 15 hours. But. That specific day, there's a little extra traffic. So it was a holiday or maybe there were some road construction.
[00:13:41] Those things would slow you down. So you might have to take a little detour. You might know, take a little slower time coming. Also, what could happen is maybe part of the road got washed away and you had to take a whole nother route around by knowing the obstacles in your way. You could still get to [00:14:00] California.
[00:14:00] You might just have to take a different way to get here, or it might take longer. So with your genes by knowing which genes could be harmful to you. We just find the detours around them. Now we know, so we won't go straight through them or we'll get stuck, right. If the road doesn't exist anymore, or traffic is so bad as at a dead stop, we've got to figure out a way around it.
[00:14:22] So that's the great thing about knowing your genes. Some people get scared of it. Like I don't want to know what's in my history. No, no, no. That's like your genes are your genes and I'll give you some examples of me here in just a second. But I love the fact that if we know. Information is power. Now we can do something about it.
[00:14:42] So whether it's a lifestyle change, whether it's a diet change, what's usual exercise change. Whether it's a, a sleep change. I mean, it could be food. It could be very easy to get around that detour, but you just don't know. And if you don't know, then you might be doing something in your [00:15:00] lifestyle to be turning on your bedroom.
[00:15:02] And if, you know, you're like, ah, I can keep them off so quickly. I'll just give you a little bit of my history is I people think I would have great genes, right? Because at 50 I've got tons of energy. I don't have access. Wait, I run a couple of businesses. I've got, you know, just great energy, but it's because I've worked really, really hard.
[00:15:23] And I know my genes. I actually have genes for obesity, diabetes, heart disease. I didn't know. I have the celiac gene, some homozygous for celiac. So I'm now completely dairy-free gluten-free I wasn't before, but again, that that's like a massive roadblock for
[00:15:43] Julie Michelson: a time bomb waiting
[00:15:44] Kellie Lupsha: That would have been a time bomb. I mean, most women at my age, if they had the homozygous gene for celiac would be super sick.
[00:15:51] With that. And several other auto that probably would have come my way. And then I also have the gene for Alzheimer's unfortunately. So knowing that I'm [00:16:00] like, oh my gosh, well, I know the, exactly what I need to do in my modifications of my life to keep those genes off. So if I, if I kind of went through life, blindly shame on me for going, oh, I knew I had that gene, but didn't do anything about it.
[00:16:16] But now I know exactly like I'm not even worried.
[00:16:20] Julie Michelson: And I love that. You're so clear. Cause I I've seen, I've heard so many people and I don't want to know head in the sand. I don't want to know. I don't want to know. Because they don't understand the power because there is this idea that your genes are your destiny and that's what we're here to talk about.
[00:16:38] They're absolutely not. And having that knowledge is exactly what allows you to make those choices, to avoid those roads.
[00:16:48] Kellie Lupsha: Yes. I mean, here's another one in our family. One of our daughters has the gene for hemochromatosis. So as a, as a young girl, when you're still going through menses each month, [00:17:00] that's really, what's going to dump your blood. You're not going to get iron overloaded, but then when she stops that she needs to know what her iron is today.
[00:17:08] And then as she ages what her iron is, and then eventually she'll start having to give blood regularly. But if she didn't know she had hemochromatosis, then she would just start feeling bad until maybe. Her organs just decided to shut down on her and she could die suddenly. But knowing that for her, as long as she monitors it, and then eventually she'll have to give blood every three months, four months, six months, whatever it is for her that should never, ever affect her life ever.
[00:17:36] But otherwise it puts so much more load on our organs. She would lead definitely to an early death of something if that was left unaddressed. So how, what a simple thing to know that could have a huge impact on her.
[00:17:48] Julie Michelson: Absolutely. Absolutely. And as you mentioned, it doesn't need to be, I mean, that's completely proactive. You don't need to wait until she's feeling sick to figure out what's going on. And so that's a, that [00:18:00] is power. That
[00:18:01] Kellie Lupsha: It is.
[00:18:02] Julie Michelson: amazing.
[00:18:03] Kellie Lupsha: And, you know you were kind of going back to some people, like, I don't want to know my jeans or your friend that called that, that you didn't know should be a potential client. And we kind of take a look at if somebody has an issue, if they're struggling with autoimmune or something versus somebody who says I'm okay, like I have nothing going on right now.
[00:18:19] Right. That this whole thing of dis-ease is just a matter of time.
[00:18:25] Julie Michelson: Oh, it's yeah. I say it's a spectrum. Really I, I, because, you know, I love the term inflammation. I've never been able to trace like who really coined that term. But it's my favorite. And because it really is all of the things you were just kind of hinting at that, that. We make the excuse, right? We though, oh, we're getting older.
[00:18:48] I should be more tired. My brain should be a little slower. Oh, I've got aches and pains. I played sports in high school. What we, those stories of excepted [00:19:00] decline. It's all, it's all inflammation based. And that is all at that gentler and of the spectrum. It's the same stuff that leads to RA cancer. The Alzheimer's you name it?
[00:19:15] Diabete. All of those things. I mean, it's all the same. And so to me, the brilliance is before you have a inkling of a symptom you know, our kids get the advantage. But they get exposed. It's just sometimes they don't, I'm laughing. Cause mine don't always think it's an advantage. They may have more information than they want. But it's the same. I say all the time working, I love working with my clients in that way. So thrilled to watch them turn their health around, but, but it's the ripple effect, right? It's the, then they're taking that and they're using it with their, their partners and their children and their family and their friends and the and so I, I [00:20:00] love this idea of you get, get the information and then you have the power,
[00:20:04] Kellie Lupsha: And then you have the power. And again, you know, I think everyone's hearing today. Like I should sleep. I need to make sure I'm breathing. I need to move my body, but a lot of people are not applying that.
[00:20:16] Julie Michelson: Well, and what you're doing is that for me, right? Like I'll, I'll take diet and that'll lead us right into, I'm going to ask you about Nutrogenomix people show up all the time and they're like, well, just tell me what you eat and I'll eat that way. You know, you healed. You're great. What do you eat? And I'm like
[00:20:32] that may not be for you.
[00:20:34] That's for me. And yeah. Things, nobody is ever going to decline in health, giving up gluten and dairy. I'll just say it right now. That's never a bad choice. And I joke I'm like that is to me, the one absolute standard, anybody with auto-immune or genes for auto-immune should not be eating gluten period.
[00:20:58] But beyond that and I [00:21:00] do, I have my. List of things that I think are fairly evil for the human body,
[00:21:06] Kellie Lupsha: Yes.
[00:21:07] Julie Michelson: but you know, I, should you be eating spinach? I don't know. Maybe, maybe not. You know, I it's it's wild. And so that's where, where, yeah, we all hear, we know these are the lifestyle areas. You know, people, people may think if there's.
[00:21:25] Sleeping, like really actually just asleep X amount of hours a night that they're doing a good thing, but are they tracking? Are they getting good sleep? Do we know what's going on? So that's, that's the, you're talking to an information junkie which is why I was so excited to have you join us today.
[00:21:43] Kellie Lupsha: Yes. Oh my God. And you guys really to understand, like you don't need to go crazy and track everything, or you can get stressed and overwhelmed about it, but if you just like, we'll take sleep. Cause you just mentioned it. And just say, if you think you can run yourself [00:22:00] ragged through the day, And go, go, go.
[00:22:02] And then even if you hit the pillow, you sleep for that seven to eight hours and you get up in the morning that, that sleep. That's the misnomer is you have to have this process of wind down and slowing down and preparing your body and allowing your body to start making those chemical changes to get you into that deep sleep and REM sleep, because that's where you heal and repair.
[00:22:23] That's where your DNA's gonna wash your brain's going to wash out the debris your DNA's gonna replicate well. If you're not in that. And then, then you've slept, but you're not actually giving your body that the heal and repair portion, which all is part of your genetics is of what you're doing. It's essential, truly.
[00:22:42] Julie Michelson: And, and yeah, to be clear, I'm a data junkie it's for me, it's, it's like that snowball effect. It's like anybody making any lifestyle change, it's the same thing. When you start testing and tracking and it's like, you know you, then you use the data to make change and you feel even [00:23:00] better. And you're like, Ooh, well, what else can I be looking at?
[00:23:03] Right. Like and it's the same in my practice. It evolved, you know, it used to be. We'd start no labs. And then maybe we do a food sensitivity panel. And then it was like, we know the always start with the food sensitivity panel and then maybe we do a full functional panel and you know, and now I, and that's because when I'm working with clients, by the time somebody shows up on my door, like they want results and we all know it's a process anyway.
[00:23:28] And I'm like, okay, we're looking at full panel. We're looking at toxins. We're looking at genetics. We're looking at labs, we're look air Food. We're looking at virus. I mean, you name it instead of like, oh, if this doesn't work, we'll look under another rock later, you know? No, Y when we have the ability, obviously financially, even with all those labs, I just named.
[00:23:52] Ton. I would love to run on everybody that, you know, nobody's going to spend the R I don't, it's not necessary to spend 10 [00:24:00] grand on labs, you know, to get information, to make change. But it does get a little it's, you know, you want to keep up leveling. And so starting with this basis of, you know, well, what what's, so I would say genes or potential.
[00:24:16] It's a roadmap, but it's potential. It's not a concrete situation.
[00:24:21] Kellie Lupsha: Exactly. And so kind of for the listeners, think like you have your genes, you'll hear peoples talking about your genome and that's, what's written in pen, right? That's what cannot be changed. That's our piano. Then we have our epigenome. And so that's really how they're going to be expressed. Right? What are you doing in your lifestyle of how those genes are going to be expressed?
[00:24:40] Meaning turned on or turned off? And the ultimate goal is to keep all of our genes. Turned on working well and our bad genes off or suppressed down. And that's going to live, allow us to function into this long, healthy health span. Right. We don't have to live longer, but we want to live healthier through this span.
[00:24:59] Julie Michelson: Yeah, [00:25:00] my, my new thing is I want to live young until I'm done. That's my.
[00:25:04] Kellie Lupsha: yeah.
[00:25:04] Julie Michelson: That's that's it. And I'm stealing. I will credit you every, but I am the piano analogy I love because I mean, that's it right? Like, so, okay. No, you can't get a new piano, but you can learn how to make it sound great.
[00:25:21] Kellie Lupsha: Yeah. I had a client of mine say he had had stage four prostate cancer and he was coming in and he was doing hyperbaric with us in a variety of things. And he told me, he said, Kelly, you know, what's so interesting is imagine if you got a car at the age of 16. But that was going to be the only car you had for your entire life.
[00:25:42] How well would you take care of that car? I mean, have you washing it and changing the oil and just, you know, rotating the T we would immaculately take care of that. So we have one body, but we miss for the most part, trash it physically, mentally everything. [00:26:00] Right. We trash this thing and expect it to run as a high-performance car, but we don't give it what it needs.
[00:26:05] Julie Michelson: Yeah. No, that's, that's amazing. I love, and for some reason, a 16, even a 16 year old. Could have that long-term vision for the car, if not thorough and body,
[00:26:19] Kellie Lupsha: Right. My kids is 17 to almost 24, and I'm really trying to tell them. You guys you're in control now. And you know, my eldest at 24, I said, you're, you're almost about as good as you're going to get. And you're going to actually start this aging process in your mid to late twenties. So like it's, it's go time.
[00:26:39] Julie Michelson: time now.
[00:26:40] Kellie Lupsha: look at your choices, right?
[00:26:42] Julie Michelson: No, it's the time. So I want to talk about, you mentioned Nutrogenomix and, and so let's dive in
[00:26:51] Kellie Lupsha: Awesome.
[00:26:52] Julie Michelson: a little we'll we'll do kind of a crash course.
[00:26:56] Kellie Lupsha: All right. You guys so nutrient genomics in, [00:27:00] in general. Okay. Without making this difficult is how nutrients affect your genes. Okay. That's like super simple. Like, does broccoli affect your genes, the food that you're taking in. W what does that do for your genes? And if you think about. Photos just information.
[00:27:18] So whether you want to have your salad, whether you're taking your supplement, whether you're eating a protein shake, the moment you take it in your body and your brain, and all of the reactions that are happening are making sense of that information. So when you're looking at Nutrogenomix it's, do you want to have these ingredients, these compounds that are going to be good for your genes or bad for your genes?
[00:27:42] So I tell people. Right. If you do, you just take sugar and broccoli, which one's going to be good and which one's going to be bad. Right. We know that sugar is going to lead to inflammation. And when I say sugar, you guys might be your bag or your cereal or your, all of it. Right. Doesn't mean like your donut.
[00:27:59] So it could be[00:28:00]
[00:28:00] Julie Michelson: although that's included.
[00:28:01] Kellie Lupsha: correct. So that's probably going to have a negative influence on your genes, right. Or you could say, wow, I'm going to go have some. You know, brussel sprouts and broccoli, an add, add that to my plate. Do you think that's going to be beneficial to your jeans or not? Yes or no? Yes. Like if you look at just something that's obvious, what are foods that are going to turn things off?
[00:28:24] What are foods that are going to nourish them? So Nutrogenomix is using these micronutrients food based compounds plant-based company. To allow your genes to do something, send them a message. And so the ultimate goal is they turn your genes on or up. So in this whole field of Nutrogenomix, there are Sutent, certain kind of superfoods and broccoli and cauliflower have been highly, you know, taught about them.
[00:28:51] Tumeric has been highly talked about in, in helping in this process, but now what they're finding Julie, which is really interesting. [00:29:00] Historically, we've been like the megadose more is better, more is better dose dose dose. So people are taking lots of things. But now they're finding that taking it is either just food or a supplement in a raw form.
[00:29:15] If you have so much of it, eventually your body's like, what am I supposed to keep doing with this? I don't even know right now, they're starting to say the deadly antioxidant. And if I can give another analogy for the listeners, if you were building a house. And somebody brought your, you know, shipment in of your raw materials.
[00:29:32] So you've got your bricks and your, you know, lumber and everything else. And then before, you know, it, somebody bringing another load of it and you're like, oh wait, where am I going to put that? And all of a sudden, somebody brought another load of it and you're like, oh my God, I have so much event. I can't even build the house anymore because it's, it's just all piled up on me sometimes if we just think.
[00:29:53] Eat eat more and more and more, or just take more and more supplements that will activate my genes. [00:30:00] The body says you're giving me so much of something. I don't know what to do with it. So instead if your body has these machines inside of us, that actually are the worker bees. Don't give the worker bees more, just raw material, make more worker bees make more like have a whole litany of, you know, construction people inside your building.
[00:30:22] So now, whatever raw material you gave it, you can actually, you have all these workers. So when we talk about Nutrogenomix and turning on genes, that's what's happening in your body, your body now, instead of working at a slow pace. It's like the, the dimmer switch of your lights over the dining room table, right?
[00:30:41] It was low now. It's like, whoa, look at all this stuff I can do because you're, you're giving the power back. You're turning the power back on. Literally you're flipping the switch of your body to turn the power back on and now your body can do the work it was designed to do. Right. You're getting rid of the trash.
[00:30:58] You're boosting your [00:31:00] mitochondria, your energy. You're turning all of those good genes back on purely using, you know, optimizing your nutrition.
[00:31:09] Julie Michelson: Amazing. Hopefully we'll sink in so much, you know, it's not just, like you said, don't eat the donut, but eat the broccoli. I love and the, the, even something where I dunno why we're picking up broccoli today. You know, more of a good thing. Isn't always better. I mean, there is such a thing as too much of a good thing, and I, I loved the visual of like just clogging things up. So next step then would be, you know, let's talk more about the worker bees. And, and I know we wanted to touch on and our for listeners today, cause I, for me. If they're like, okay, but you know, what do I do? Or this is great. Or, you know, I thought you [00:32:00] said this was going to be really unusual. So I want to talk about NRF two or Nerf two.
[00:32:05] However people may have heard activation. If there's such a thing is keeping it kind of brief. Cause I know we're like so close to end of time. I know I'm like, oh, do I just have her come back and we'll do it just a separate one on that, but let's touch on it
[00:32:20] Kellie Lupsha: Let's on.
[00:32:21] Julie Michelson: yeah,
[00:32:22] Kellie Lupsha: You know, what if this is your first time hearing it, or maybe you've heard of it before. It's always good that second and third time to start having a deeper understanding. So it's all good, even if you've heard it before. So there is a pathway in the body called NRF two. Sometimes when people say Nerf, two people go like Nerf, like a Nerf football or a Nerf.
[00:32:40] What are you saying? So it was literally the letters you guys, N R F and then the number two nerve to. This pathway has been coined are deemed as the master regulator of gene expression. So this pathway keeps your good genes on and keeps your bad genes [00:33:00] off. That's the job of. So when we're young, when we're born or when we're young and when you're relatively healthy, that Nerf two pathway is working optimally.
[00:33:11] And as we age, it starts to slow down G but also even as you age, because we're exposed to so many pollutants, toxins chemicals, we're running ourselves ragged with poor sleep and maybe poor diet. That's actually going to slow it down even more. And so therefore some people that's maybe why auto-immune gets turned on earlier than it should, or it gets turned on at all.
[00:33:36] That's why some people start having chronic disease earlier, or maybe that's why cancer's crept into your life. And so this nerve two pathway literally is. Is one of the number one things to keep, even if you're eating well, doing all the right things, you also want to optimize this pathway. And so you don't need to know all the [00:34:00] complex of what's happening in the pathway.
[00:34:02] Really for most, all of us is knowing that if this pathway is one of the most important things that we can do to keep our genes working, optimally, how do we turn on this nerve to pathway it? We didn't even hardly know about this. Everyone, like before 20 years ago, it's all been discovered that. Discovering the human genome, right project and everything got map learning how to turn genes on and off learning that we're in control of them and learning that there is a master switch in the body called NRF two to help us normally regulate this it's like that thermostat.
[00:34:37] And so just like. Exercise to help boost that there's foods that help boost that there are, there are also now quote products like a supplement, meaning you swallow them. But instead of a supplement, they activate those genes. They keep your pathways like NRF two working. Well, there are other pathways and today's not the day [00:35:00] to talk about like the NRF one pathway supports mitochondria.
[00:35:02] We have pathways supporting NAD and your longevity sirtuins, but for now just think, wow, if I could give my body one thing to make. I'll say work like it was when we were young. Ultimately that's what you want is your genes to stay working so that you can live young until you don't want it until you're done like that until you're done, that would wait.
[00:35:26] That would be to flip the switch of NRF two and I will say. There was a literature review that came out in 2015 by Washington state university. And they, their claim of this 20 page literature review of nerve two said that this may be the biggest breakthrough in the history of preventative measures.
[00:35:46] And it's like, wow. When we're really going down that whole road of wellness and prevention, it may be simpler than when we all thought it doesn't have to be as complicated as we want to make it. If we don't have to reverse illness and we can just, [00:36:00] and then we can just keep wellness. Like, it's amazing how well we can stay if we never were sick in the first place.
[00:36:06] Julie Michelson: absolutely. And I think it's even more amazing how well we can get, even if we've been very sick in the first. I mean, it is it's remarkable. So I have no doubt as somebody who went from, you know, them trying to get me to put a handicap placard on my car to how physically active I am now. And pain-free and well, and healthy and happy, and life is full too.
[00:36:33] We're back to the 16 year old, right. Or the 24 year old, or, you know, our kids are minor right in that same age group as yours. And it's like, You don't need to go there. And I know if we can, if you can reverse as much illness as I had, there's no question you can prevent it. It's just, and we see it all the time.
[00:36:54] I mean, it's not just me. I'm not special guys. I really not. That's the whole reason [00:37:00] we're here talking is we can all do it.
[00:37:02] Kellie Lupsha: We can all do it. And I will just tell everyone, because most of the time, when I have a conversation with somebody who's not sick, they're like, I feel.
[00:37:13] Julie Michelson: Right.
[00:37:14] Kellie Lupsha: I don't, I don't need it. And all I will say is to the listeners out there that I now use. I used to say the word fine a lot, and I have now changed it.
[00:37:23] That that's my four letter F word. And I can't say fine.
[00:37:26] Julie Michelson: I love that. I, my I'm going to, I would like to pretend my partner listens to all of these episodes, but he's not allowed to use that word. I have taken it out of his vocabulary. So that's a I'm right there with you.
[00:37:39] Kellie Lupsha: And the thing is, is to all of you listeners out there, you'll be amazed at how often you say the word fine. And if you can actually replace it with what you're really meaning or feeling at the moment, be specific, you, it will change so much and you'll have a greater appreciation because none of us should live feeling fine.
[00:37:58] Julie Michelson: Yeah. Well, and here's, that [00:38:00] goes back to, I mentioned that conversation. I had the, you know, for those of you that are like, oh, but I, I can hear them now. Oh. But I do feel fine. Okay. You don't want more energy. You don't want to be stronger. You don't, your GI system couldn't work better. Your brain couldn't be sharper.
[00:38:17] You, I mean, the list goes on and on and on of why again, why don't settle for normal and whatever fine means to you in a given moment. Don't settle for that either.
[00:38:28] Kellie Lupsha: And fine is the middle of that. Teeter-totter right. So if you're really only fine, it's you're on that tipping point of not.
[00:38:36] Julie Michelson: Well, and some people I think fine is a very broad part of the pendulum there, you know, like you really find could be, you're really all so far into the not fine, but you're just not willing to say it, you know, or it could be. So, you know, today was amazing. I, so I didn't take that word away actually, related to health in general, it [00:39:00] was more like, how was your day?
[00:39:01] It was something, how you feeling? How just leave. How's your day? Fine. Fine, fine. I'm like, no, no, not, not. What does that mean? No. So I love that. That's where he
[00:39:11] Kellie Lupsha: Oh my gosh. And you I'll just end for your listeners that, you know, I've I've been very fortunate to help. A handful of people have recover from some devastating illnesses or injuries. But what I found through all of my time, working with people that there are people that have all the money in the world and they would give anything to get their health back.
[00:39:31] So I will just tell all of you. If you're not doing one thing to just do that one thing to make your health better today shame on you, knowing that you can, and you're capable because once you've lost. It's very, very difficult. And so just honor yourself by just taking one step in the right direction, whether that's your food, your sleep, whether that's learning about turning on your NRF, two pathway, whatever that is, but take one thing, pause [00:40:00] in the positive direction towards your health today.
[00:40:02] Julie Michelson: Well, I love that. And you teed up my final question, which is what is one step. Now you're going to have to pick one. I know, but what is one step that listeners can do today? The thing that they can just start, that will start to move that needle in the right direction.
[00:40:19] Kellie Lupsha: Yeah, it's really such a great question. The great thing about the body is we are given beautiful gifts that we have within us that is 100% free that we can all do. And so, even though as a physical therapist, I always want to say movement because our bodies were meant to move. But what I will say that I'm learning one of the biggest things, because we know we should exercise and we know we should eat.
[00:40:43] Right. But what we rarely talk about is just the power of. And the power of breathing about allowing yourself to be present for the moment because that will help rebalance your system from most of us [00:41:00] in our day-to-day moving quickly stress and burnout coming, right. We've, we've learned and trained ourselves to not pause and to not breathe.
[00:41:08] And if you can just give yourself time in your day. It doesn't need to be 30 minutes of meditation. It can just be 30 seconds a couple of times a day to get your breath back, work on breathing. That is probably one of the most powerful things that you have with you all the time that can lead to really, really big influences in your long-term health.
[00:41:30] Julie Michelson: I love that. I love. That's why I love it. Yeah. Because I am always, so I never know like what, there's so many good answers. But th and there's, we can die and I have done, I was gonna say we could do podcasts on the, but we, I have done, I think, two or three episodes ready on breathing and breath. And, and so I love that.
[00:41:49] That's where you went with. This is amazing. I will have your information in the show notes. Oh, and I know you also, you have a gift [00:42:00] for the audio.
[00:42:01] Kellie Lupsha: I do.
[00:42:02] Julie Michelson: which will be linked in the show notes as well. Tell me, tell us a little bit about your gifts, the taking, take the guesswork out of aging.
[00:42:10] Kellie Lupsha: Take the guesswork out of aging. Right. You know, hopefully, hopefully you were listening to the past, up 30 minutes to Julie and I had together and you're excited to learn about your blueprint, but really I want to, I think you'll be surprised at the things that you can find in knowing your DNA. And even just silly things like, you know, should you drink caffeine or not for your body?
[00:42:31] What about salt in your body? What about like, wow, I take vitamin D or I'm out in the sunshine all the time. Why is my vitamin D so low? It will really empower you. And so take, take, it's a, it's not really a quiz. It's going to tell you like some top 10 things that you're going to learn. And that's some direction that I hope each and every one of you guys can take really take the next steps in moving forward in your health, because it's exciting.
[00:42:55] I mean, these are times 20 years ago, we didn't have this capability, but [00:43:00] now we do. And it used to be. You know, tens and thousands of dollars to get all this stuff done. And now it doesn't have to be, so don't wait, don't wait.
[00:43:10] Julie Michelson: I love that. That is amazing. Where's the best place for listeners to find you? I know we've, we've got all the places in there, but you know, if they're like me, I always listening to podcasts on the go. So where's the number one. They want to know more about Kellie.
[00:43:26] Kellie Lupsha: Thank you. Facebook or Instagram. You can also actually even find me on Tik TOK, but Kellie Lupsha. And I'm the only Kellie with an I E. K E L L I E. And my last name is L U P S H A. I'm @thewomenslongevityexpert, but if you just plug in my name to any of those platforms, I'll pop right up.
[00:43:45] Julie Michelson: Wonderful Kelly, thank you so much. You've shared some amazing tips and real gold with us today. You've empowered listeners. If they take action on any of the many amazing things, you've told them they will [00:44:00] definitely improve their life.
[00:44:01] Kellie Lupsha: Your genes will thank you, you guys. So Julie is a pleasure. Thank you so much for having me on.
[00:44:05] Julie Michelson: For everyone listening. Remember you can get the show notes and transcripts by visiting inspiredliving.show. I hope you had a great time and enjoyed this episode as much as I did. I'll see you all next week.