Episode 63
James Schmachtenberger:
It's Time to Manage Your Zombie Cells
In this episode, we talk about how to reduce the number of senescent cells to live younger. The inspiring James Schmachtenberger joins us to guide us through what we need to know about our zombie cells and how to use this knowledge to our advantage.
First Aired on: Nov 28, 2022
Episode 63
James Schmachtenberger:
It's Time to Manage Your Zombie Cells
In this episode, we talk about how to reduce the number of senescent cells to live younger. The inspiring James Schmachtenberger joins us to guide us through what we need to know about our zombie cells and how to use this knowledge to our advantage.
First Aired on: Nov 28, 2022
Table of Contents:
In this episode:
James Schmachtenberger is a successful serial entrepreneur, with a lifelong focus on using business and innovation to effect large-scale change for the benefit of humanity. He is the co-founder and CEO Neurohacker Collective, a company focused on making groundbreaking products for health and well-being through complex systems science. His areas of expertise include nootropics, anti-aging and regenerative medicine, sleep, and fast-paced entrepreneurialism.
James shares his story with us, beginning with his mother’s journey with interstitial cystitis, which nearly killed her when he was a young boy. His mom found alternative medicine, recovered, and learned that sometimes allopathy isn’t the answer to our health challenges.
Through his first entrepreneurial experience of working himself to sickness, as the owner of a school, James learned first-hand, at age 21, how it feels to be exhausted, suffering from brain fog, depression, and existential challenge.
He sought novel IV treatment at a clinic in Mexico, where he was completely turned around after 3 days and experienced an overwhelming sense of empathy.
This experience greatly shaped what is now Neurohacker Collective, as well as his mission to truly contribute to making the world a better place.
Senescent cells are no longer dividing and contributing, but haven’t died off.
Not only are they consuming valuable resources, but they also encourage senescence in other cells.
Hence the term zombie cells.
Improving health at a cellular level has a net-net benefit.
Senolytic studies by Mayo Clinic and Scripps highlighted targeted approaches to reducing senescent cells and that was the starting point for the research into Senelytic.
Different cells types are best targeted by different substances and that’s is where this product really shines. By combining these substances in a way to enhance the whole body.
Senolytic is used as a “hit and run” therapy.
By cycling the supplement using it two days in a row, once a month, it is most effective at “pruning” those senescent cells.
Ideally, it is used as an enhancement to healthy lifestyle that includes good sleep, clean diet rich in polyphenols, intermittent fasting, and optimal exercise.
It is not a remedy for the big mac!
James shares his story with us, beginning with his mother’s journey with interstitial cystitis, which nearly killed her when he was a young boy. His mom found alternative medicine, recovered, and learned that sometimes allopathy isn’t the answer to our health challenges.
Through his first entrepreneurial experience of working himself to sickness, as the owner of a school, James learned first-hand, at age 21, how it feels to be exhausted, suffering from brain fog, depression, and existential challenge.
He sought novel IV treatment at a clinic in Mexico, where he was completely turned around after 3 days and experienced an overwhelming sense of empathy.
This experience greatly shaped what is now Neurohacker Collective, as well as his mission to truly contribute to making the world a better place.
Let’s talk about senescence!
Our cells have a life span and, ideally, through apoptosis they die off and free up resources for healthy cells.Senescent cells are no longer dividing and contributing, but haven’t died off.
Not only are they consuming valuable resources, but they also encourage senescence in other cells.
Hence the term zombie cells.
Health Span
Cell senescence is one of the 9 Hallmarks of Aging.Improving health at a cellular level has a net-net benefit.
Anti-aging isn’t just living longer…
It’s living better.Senolytic studies by Mayo Clinic and Scripps highlighted targeted approaches to reducing senescent cells and that was the starting point for the research into Senelytic.
Different cells types are best targeted by different substances and that’s is where this product really shines. By combining these substances in a way to enhance the whole body.
Senolytic is used as a “hit and run” therapy.
By cycling the supplement using it two days in a row, once a month, it is most effective at “pruning” those senescent cells.
Ideally, it is used as an enhancement to healthy lifestyle that includes good sleep, clean diet rich in polyphenols, intermittent fasting, and optimal exercise.
It is not a remedy for the big mac!
James’s 1 Thing…
Pursue that which makes you feel most alive! And that will fuel the rest.
Other Resources:
Connect with James Schmachtenberger
James Schmachtenberger has a gift for you!
15% off Neurohacker
Use coupon code INSPIRED to receive 15% off any purchase at Neurohacker.
Episode Transcript
Julie Michelson: [Page//00:00:00] Welcome back to The Inspired Living with Auto Immunity podcast. I'm your host, Julie Michaelson, and today we're joined by James Schmactenberger, co-founder and CEO of their Neurohacker Collective, a company focused on making groundbreaking products for health and wellbeing through complex systems science.
James brings his lifelong focus on using [Page//00:01:00] business and innovation to affect large scale change for the benefit of humanity. Today's conversation focuses on senescent cells or zombie cells, and how using SY Alytics may be the anti-aging key you are looking for.
James, welcome to the podcast.
James S: Thank you. It's a delight to be here,
Julie Michelson: I would love for you to share a little bit of your story with people before I hit record. I was kind of, well, to me you're a celebrity . But, but I, I want people to really kind of just get an idea of how you got to be making the contribution you are and, and what, you know, what brought you to this world.
James S: Yeah, yeah. No, absolutely. And it's funny cause you know, there's of course so many different parts to the story, right? But guess I'll just say like the holistic medicine has been kind of a life passion for me from very, very young My, my mom has a disease called interstitial cystitis, and she had [Page//00:02:00] done, she had participated in a drug trial when I was like five years old, and it nearly killed her.
And she ended up in the hospital for I think, like three months. And, you know, was very close to death, even if she was gonna recover, was never supposed to walk again. And like she. Pro ice skater, you know, prior to this. And so, I mean, obviously huge contrast. And when she was in the hospital somebody had given her a book on Iveta medicine and she had nothing else to do, so she devoured the book, ended up finding solutions and, you know, kind of eventually left the hospital and went down this natural health track.
Got. You know, dramatically better and a year later was competing in ice shows again. And so like that was a kind of key turning point for I think me and my whole family, where it was like, okay, medicine in this traditional form has incredible applications and. It deeply lacks in some key areas. And taking a more cutting [Page//00:03:00] edge, more alternative kind of approach can oftentimes do as much, if not more than a path you can.
So that, I mean, really set a tone for the rest of life. But I think, you know, as, as it pertains kind of like to why, why narrow hacker, right? Why do we start Poly? That story really was. When, So when I was 18, I was in school at a vocational college studying alternative medicine and psychology. And right around the time I was graduating, the owner of the school, the founder of the school had said he wanted to semiretired.
Cause I wanted to teach, but he didn't want to run the business anymore. So in my 18 year old hub, I was like, Oh, I can do this. So I went out and raised money, which God knows why anyone gave me money at that age. And I bought the. And it was phenomenal. I was like incredibly passionate about the work.
It was definitely what I wanted to be doing with my life, but I had no skills. Like I didn't even know how to balance a checkbook. So here I am all of a sudden [Page//00:04:00] like 18 year old kid doesn't know didly and now I'm running a school. And so I made up for the lack of skill with just pure work. And, you know, 20, 22 hour days, take a short nap at my desk. What's that?
Julie Michelson: the American Dream.
James S: Exactly. I think we might need to update that dream.
Julie Michelson: Yeah. There is a better way. Heads neuro, hacker,
James S: it, it, it definitely took me some years to learn it, but I, I do not recommend pushing that hard, even at that age where you're almost bionic. But
Julie Michelson: or think you are. Yeah.
James S: Yeah, at least think you are. But yeah, so you know, I, after about three years of just ridiculous workload at 21, I had severe burnout. And I was like, I started having massive brain fog.
My memory stopped working. I started going into depression, which I was doing this work that I was deeply passionate about, and I was depressed. So then I started having an existential breakdown, like [Page//00:05:00] couldn't make sense of life. So I went on my healing journey. And you know, being in the field, I was fortunate to get exposed to a bunch of things and try all kinds of stuff.
But there was one therapy particularly that. Changed my world. And it, it was, I ended up going down to Mexico and doing this sort of experimental intravenous therapy that at the time I had no idea what it was. Later on, I realized it was high dose in ad and a combination of a bunch of acids. But I did three days of this drip for like nine hours a day, and it changed everyth.
And not in like a subtle way. Right. And f I mean, I went in depressed, unable to think, unable to retain thoughts and coming out I. Not only had all of my cognitive function back, but I was experiencing a sense of clarity that I had never experienced before. I had a sense of like capacity and motivation that was unlike anything that I had [Page//00:06:00] ever felt.
And then the thing that was super remarkable for me was my sense of empathy shot through the roof. And it, it became the situational where it was like I couldn't think about what I wanted to do in the world and not immediately be aware of the implications of that on the rest of the world and the people around me.
And so as I was sitting there, I was like, Holy shit, what would happen if this became available at scale? Right? If we could build something that would allow, you know, hundreds of thousands, millions of people to become drastically more intelligent, more confident, more capable, but also more empathetic. So, They had an intrinsic motive to use that competency and that intelligence, not only for personal gain, but for the greater good.
Like, ah,
Julie Michelson: World changing.
James S: so this was, this was the concept, right? And initially I actually tried to partner with the doctor who created that IV therapy. We were gonna open clinics. Unfortunately, like three weeks into that project, he became super ill and passed away and his research went away with, [Page//00:07:00] So here I was with this beautiful vision and no path.
And so then I spent several years while, you know, running other businesses, new other things, interviewing all the top neuroscientists, neurobiologists, chemists, formulators, and everyone was like, Yeah, this is a great concept. It's not doable. And and I just couldn't let it go. Right.
Julie Michelson: Thank you , for not letting it go.
James S: Yeah, so it was, it took me a long time, but eventually I ended up convincing my brother to partner with me and I had tried for years and he kept saying no. But he's, you know, a lot of people have probably seen him on podcasts. But he's one of the rare geniuses of the world and his background is in complex system science.
And I knew that if we could apply complex system science to the study of physiology, we could do things that the world had sort of never seen before in terms of healing and health optimization. And so eventually he agreed to partner. We dove into this like [Page//00:08:00] two year full on r and d process, both sort of developing.
Scientific model based on complex system science but also developing the first product, which was quality, right? Our broad spectrum cognitive enhancement. And that was essentially the, the birth of Neurohacker was A, you know, lofty vision, some semblance of tenacity that eventually panned out and, and seen amount of research.
And, you know, luckily it's, it's been a pretty extraordinary ride and process and, you know, given the opportunity to help a lot of people and hopefully more to come.
Julie Michelson: Which is, is incredible. I was telling you before we started, I have been a, a long time fan of the company, an early adopter, if you will. And I, I love. I always say my, my start in biohacking that led me to, to functional medicine, you know, the, the two worlds are, they really are, to me, [Page//00:09:00] ideal. Is it, It's both, right?
The best functional medicine docs are pulling from biohacking, and if you're biohacking properly, you're utilizing functional medicine. And so there's a synergy there. And so I love when I first found Colia the mind. I did, other than my group of biohacker. Like I didn't know anybody else taking it.
I did, you know, nobody else had heard of it. And, and so I love, now you know, how the company has grown. And I, you have, I I would love to do an interview for each of the products. I did share, you know, I am a, I am, not only do I love the contribution that the company is making by. Truly creating these products, you know, with not even just the, the science you pull together.
But. Your process of getting stuff to market and, and testing and, and you do have a group of us that are well, we're willing to, [Page//00:10:00] to be Guinea pigs and try, there's a trust level there so that you guys can tweak and continue to improve your products which is amazing. We're gonna jump, So I say anybody who's like, you know, what is this Neuro Hucker collective and what is Pia?
Look it up. I just learned. From a presentation this past weekend, I, I never even thought about it, like, what is the definition of Lia? And I was like, Oh, this makes so much sense. If somebody wants to know, well, like, how does a neutropic and a sleep enhancer and a lytic all tie together? Like, how is this one company?
But if you go back to colia, this, which is the experiential quality, Of what is like to be you. It's like. This is it, right? Like it's best mind, but you know, this is so, so thank you, thank you, thank you from the bottom of my heart for what you guys are doing and how you're doing it. And I [Page//00:11:00] want to jump into, This, you know, your newest product which I really do.
I, I, for me, obviously your first product changed my life because I still, When did that come out? I don't even know how many, how long I've been taking it.
James S: Quality of mind was our first one, and that came out in late 2016.
Julie Michelson: Okay. That makes sense.
James S: Entry into the world. Yeah, it's been a little bit now.
Julie Michelson: Yeah. And, and so, you know, that's a commitment. So I've, I've been, you know, using that ever, ever since then. But I, I real so that, you know, I know each, each product has the ability to change your life. You know, if I, and I always say, you know, it all comes down to if we're sleeping better, that quality of sleep, getting your mind to work.
But I'm really. Because of the, more of the, even the functional medicine piece. Excited about your latest and greatest. So [Page//00:12:00] let's talk a little bit about SCE essence and SY Analytics and what this is. Why are we even talking about it on an, an autoimmunity targeted podcast? You know, why does, you know?
Cause you're, you don't make products for three people. You know, it, it's really something that can enhance everybody's.
James S: Yeah, absolutely. I mean, it's interesting cause right, this whole area of cellular in essence like is so new people, I mean, most people that are listening right now have probably never even heard
Julie Michelson: That they won't even know. So let's even, let's start right there. What is sin Essence?
James S: Yeah. Yeah. So basically, Healthy cells are supposed to be able to continue to divide and reproduce, right? And then once they get to a point where they no longer have the ability to continue to divide and reproduce, then they're supposed to die off. Right? That's a process called apoptosis and. That's how the body sort of operates healthy.
But [Page//00:13:00] what ends up happening as we age and as we have more stressors and poor nutrition and, you know, various different things, is that oftentimes cells will become what's known as senescent or like commonly it's referred to as zombie cells, right? And what, mm-hmm.
Julie Michelson: me is like the perfect. For people to understand when you say zombie cells,
James S: Yeah, I mean, it makes perfect sense when you actually get to understand how it works, right? So basically a cell will get to a place where it's no longer able to divide and reproduce, but it doesn't die off. And so it's sort of alive, but it's not really doing anything. It no longer is able to do much in the way of energy output.
It doesn't have a lot of the beneficial. Traits that a cell normally does. So it's just sort of pseudo living, taking up resources. But part of why it's also called a zombie cell is it's not, It's not just the problem of it taking up resources and not providing benefit. It's also that it AITs certain proteins that turn the other cells [Page//00:14:00] around them into esent cells.
So in the same way that a zombie will try to eat your brains and it turns you into a zombie, right? These esent cells emit these chemicals, which then turn other ones into it, and that whole process drastically speeds up the aging process. And so this is essentially what you know, cellular esce is, and in the term sen lytic, which we'll be talking about a little bit, are the compounds that are researched for being able to kill off esent cells, right?
Being able to allow them to actually finish their life cycle and die off and make space for new healthy cells to be able to reproduce.
Julie Michelson: Which I, and I, I, again, I love the like, simple, I'm not a scientist . And so
James S: I'm not either. I just play one on
Julie Michelson: Yeah, when I, when I, and I'm, I know, I'm saying, I always say that I'm not a doctor and I don't play one on tv, . But if you, if you think of, you know, it's a cleanup, right? Like this is what we're talking about. And, and I like that you, you know, To, to take the zombie [Page//00:15:00] thing all the way that it's not joke, cuz I always kind of thought of it.
And so I learned a lot at the quality of presentation, the, this last weekend because I always thought of it kind of as just the first piece, right? I know we, you know, we get these esent cells and we, we want them gone, but they're not dying off. They're taking resources. I think of it. You know, I have a lot of house plants and I love to garden and, and so the pruning right?
We wanna get rid of those dead and dying leaves so that the, the rest of the plant is, is getting the good stuff. But then when you understand this kind of it thing, I think of it as like building a cellular army. We don't want, we don't want more and more of ourselves just hanging out, you know, grabbing buddies.
And I, I, I want to just for the audience's sake cuz some people may think like, anti, I'm not interested in anti-aging. Like, I just wanna feel well, I say this all the time to me the things [Page//00:16:00] we think of, the negative pieces of what we think of as aging is all, in my opinion, my humble just said, I'm not a scientist or a doctor
But it's all inflammation. That's why we, you know, my favorite word is inflammaging. And I, I wish I could figure out who actually coined it, cuz I can't, like, I've never been able to find out who the first person was to say that in public. And to me, autoimmunity is just further down the spectrum on that expression of inflammation.
And so by focusing anything we can do, To reduce inflammation to, you know, help reverse the aging process or add some grace to it is also the same things we need to be doing to improve our autoimmune symptoms and, and live fuller lives.
James S: I mean, this is sort of the beauty of the, the domain of like anti-aging research, right? Which this scene alytics fall squarely within that is, it's not just about. It's not [Page//00:17:00] anti-aging exclusively in the ways that people typically think about that, which is either how do you live longer or how do you look better for longer, right?
Like, these are both key things. And of course they're, they're good goals to pursue.
Julie Michelson: in a, in a way, but there's the piece of, I, my, the thing that fell outta my mouth on a podcast that I was like, Oh, I'm writing that down, is I, I wanna live young until I die. Like I, honestly, it's not about used to be about how long I live, cuz I didn't think I'd live to see 50. Now that I'm 53 and I feel younger than I did at 34, like, I just wanna live like this until I'm done.
Like, that's the, That's what we're talking about is that quality of life.
James S: Yeah, I mean, people get so focused on lifespan, right? How many years you're on the planet, and that's awesome. But like what we tend to focus more on is what we refer to as health span, right? How many years are you on the planet and thriving in health? Because even if we can develop [Page//00:18:00] technologies that allow for you to add, you know, 5, 10, 20 years to your life, but those last years are bedridden in pain, that's not actually a goal that most people are that attracted to.
Julie Michelson: No. Nor should
James S: we.
Julie Michelson: be
James S: Add and ears that are thriving health or, you know, don't even worry about adding ears. Just improve the quality of life during the time that you're here. And the beauty of so much of the stuff in the anti-aging space is like a lot of that work is being done at the cellular level. Right. That's one of the key things here in cellular senescence, right?
So when you're improving health at the cellular level, you're essentially going to improve everything because it is like the fundamental building block. And so, yes, there's of course things you wanna focus on depending on what your needs and conditions are to address specific. Symptoms to address specific parts of the body.
But when you can improve cellular health overall, there's just this net net benefit across everything. You feel [Page//00:19:00] better, you have more energy, more clarity of thinking. You heal faster. Like virtually
Julie Michelson: become a better human, which is, goes back to your story of, and know you're empathetic. You're, it's a, it becomes about, And not just survival. And, and so, you know, that's why we're having this conversation today. I'm, I'm excited about. So let's talk a little bit about SY Analytics and, and, and talk about how this is different, Right?
I, I just said I've been using your first product since I found it, which I believe was right away in 2016. Definitely by 2017, but I, I think it might have been 2016. I take that on a regular basis. And so let's kind of talk about this cycle of. You know, guide us through the, this amazing kind of cutting edge being involved in the anti-aging world.
You know, there are, this is, it's [Page//00:20:00] new, but it's not new, right? Like this, this idea. And there are prescriptions that have been used. There are what's new is that you're, this is accessible and, and effective and so, People can take charge. I'm all about giving, giving, creating power, right? Empowering people.
So let's talk about the, the actual product and. Kind of the, not the, the, the science behind it because we don't have enough time. And I don't know if I have the, well, I do have the brain power. I took my mind this morning. But you know what, it's because it is, it's a very, it's very different. And I think that the way you guys help us understand the, like, okay, why we're taking it and then how it works.
Is it, it that just makes sense.
James S: Yeah. So I mean, I guess like if we dive in, there's So cellular in essence, is one of what's known as the hallmarks of aging, right? There's, there's nine hallmarks of aging, and these are like the key areas that [Page//00:21:00] cause the aging process. And there's extensive research going into all of them. Some, you know, the world understands better than others.
Some we have more tools to be able to affect than others. But things like, so like cellular essence is one of them. Mitochondrial function is one of them. Stem cell exhaustion is one of them. Telomere length, right? So there, there's all these different hallmarks. There's like, for Neurohacker, there's two primary ones that we've dod deeply into so far, which is cellular, senescence, and mitochondrial function, right?
So we have another product called Quality of Life, which is this just phenomenal mitochondrial function product helps to improve. Cellular energy output, cellular metabolism dramatically boosts an ad levels like all kinds of cool stuff. As we move into cellulars essence, part of what makes this domain so exciting is it's ridiculously new.
And so like this is one of the first times in history where there's something available to actually have an impact here. So, Like the field of Esce has been [Page//00:22:00] researched for several decades now. Like we've known that these esent cells exist and we've known that they cause problems. But that was kind of the extent of what the research community understood, and there was never this understanding of, well, anything can be done about it.
And that was some really breakthrough research that only happened in 2015. Right. So this is super recent.
Julie Michelson: yeah.
James S: It was predominantly from Mayo Clinic and from scripts where they began using actually it was a drug trial with a drug called the stib, which is cancer drug. But what they found was that when they were giving patients the stib and then biopsying the tissues, they were starting to see dramatically less.
Esent cells. And then there started to be some other research where they were using dasatinib and corin to supplement that a lot of people probably have some familiarity with. And then you saw, you know, an even greater decrease. And so it's, it's only in the last, what is it, seven years, that there was any awareness that something could be done [Page//00:23:00] and.
Dasatinib definitely shows really promising results in this area, but it's also a pretty harsh drug that has serious consequences, and so that's where, you know, then the next stage of research started to began of, well, what else could mimic some of these effects? And do it with creating all the benefit, but without creating harm.
Right. And so then there started to be some studies with a number of other compounds, but particularly the two most research, most known are Cetin and Corin. And these are both, you know, somewhat commonly available supplements. And you know, all coming from plant extracts that show drastic decreases in the amount of esent cells in the body.
And then where the research has continued to evolve, and this is, you know, where we've been able to do some really, really interesting things is. So there's different, there's esent cells in all of the different types of tissue in the body, [Page//00:24:00] and this is something that a lot of the research community isn't actually even paying attention to yet.
But you have esent cells in, you know, skin tissue and in muscle tissue, and different compounds end up being able to kill off cells in different kinds of tissues more effectively. So, You know, there's, there's really not that much on the market right now. Around r are usually only one or two ingredients, and so they're effective, but they're predominantly killing esent cells in particular tissue types and not necessarily addressing whole body. And this is, as you know, like our approach is this whole systems's approach, right?
We're always looking to not just affect one or two narrow things, but how do we do this whole system upgrade? So we did this deep dive into research and found all of the compounds that had really meaningful backing for being able to address cells and all the different tissues and then put them all together, , right?
And
Julie Michelson: What a concept[Page//00:25:00]
James S: Yeah, and I mean, and I understand why a lot of companies don't do it, cuz I mean, it does take dramatically more hours of research. And you know, as you start using more ingredients, it's more expensive to produce. It's. More complicated to actually run through machinery. There's, there's lots of challenges, but for us, the goal has always been how do we make the very best thing that can exist and we'll figure out how to address the difficulties in getting there.
And so it's just become this phenomenal, phenomenal product where people are showing tremendous benefit in really short periods of time. Like kind of remarkably simple.
Julie Michelson: Which is amazing and
James S: I.
Julie Michelson: Oh, we had a little,
James S: Yeah, I mean we, you know, this product's only been, I think three. Are we, Do we
Julie Michelson: No, we're good. We're good. We're back. [Page//00:26:00] So the product just is new.
James S: you know. Yeah, so the etic product is quite new. It's only been out three months or so. So we're still continuing to do all kinds of follow up studies, but we did one study initially that was really compelling where, so one of the key areas where CYS and Cells will show up, that people will notice is joint health.
Right. As you start to have this build up of, of these unhealthy ENT cells, it tends to create things like, Joints, stiffness, pain, lack of mobility. So we, we did a study on that specifically, and what we found was over the course of people doing this product three cycles we found a 53% decrease in joint discomfort.
And a 51% decrease in difficulty doing regular tasks. And that's dramatic, right? Like cuz I mean, this was a very short period of time. We're talking under three months. And you know, [Page//00:27:00] for a lot of the people that were involved in the study, like the challenges they had were fairly significant. And all of a sudden now there's half of that.
Julie Michelson: Which is amazing. This was a group in their seventies? Yes.
James S: It, it ranged. Like with all of our studies, we, we generally try to get a pretty healthy range of both, you know, age, gender, everything. But yes, in this one we did air a little bit on the older side cuz that's where people
Julie Michelson: get your symptoms.
James S: noticeable effects.
Julie Michelson: Yeah. And that's something I wanna, I, I'm always, I'm very big on, you know, markers and tests where you can, and, and you, you mentioned it when you're talking about the earlier, you know how the studying Right now to truly see, you know, what's going on with the cells, you're talking biopsies is, nobody's gonna be going in.
Oh, I'm trying this new supplement and I'm gonna go in and get biopsied every three to six months to see what it's doing. But the remarkable thing is, as you mentioned already, you know, just the improvement and in quality of [Page//00:28:00] life and hitting so it is, is noticeable for, for people. You mentioned cycles, and I, I think this is so important to talk about this.
This is something that I think a lot of people aren't used to as far as how, how you use the product effectively,
James S: That a few minutes ago when you talked about pruning, right? So with most supplements, people are used to the idea that you take them all the time, right? You take 'em every day or you take 'em a few days a week. But when it comes to addressing esent cells, the research actually shows that the best way to address them is what's often referred to as the hit and run approach, right?
You do a large amount of this lytic compound. For a very short period of time, and then you take a break and then you do it again. Right? So the lytic product we developed is, it's essentially like a cellular cleanse. You do it two days on and then wait a month and then do it again. And [Page//00:29:00] it, it's very much like that pruning process, right?
Like if you had. Plant that had some yellow or dying leaves. If you were to actually go and prune it every single day for just a little tiny bit, it would actually take up way more resources from the plant and be counterproductive versus allowing a little bit of time to pass for more yellowing. And then you go and you prune those leaves.
And so it's that exact same process when you're talking about clearing out esent cells. And I think this is one of the reasons people have also liked the product. Actually, as you and I were talking about before the interview started, so many people struggle with consistency, right? You wanna take supplements, you know they're going to have benefit, but you know, do you build them into your lifestyle and remember to actually do it every day?
And so one of the cool things with this analytic is you don't actually have to, right? You take it two days and then you're off for a month and then you take it again. And that's sort of like, that's the recommended approach. Some people will wait longer. It obviously depends. You know [Page//00:30:00] how much cellular, in essence you think you have built up, how important it is to work on it.
You can do two days and then wait three months, but the sort of ideal is this sort of like monthly cellular detox.
Julie Michelson: Yeah. Which is also, you know, that's the coach in me is like, that works on the calendar. You know, my, my dogs get an, an injection. I give them a supplement for their joints once a month, you know, so, The beginning of the month, I'm already thinking like, Oh, this will go . You know, this will be my beginning to pay your mortgage and , take your lytic.
Which I love. One question that comes up a lot. I know because I got to listen to the questions in the, in the presentation last week is about, you know, additional behaviors or lifestyle adjustments of like, really is this gonna work if I'm just. Taking the supplements, Is there other things people should be doing to improve results or, you know, have in mind of [Page//00:31:00] like, okay, if, if we're now aware, like we really want this cellular clean out and optimization, what else should we be doing?
James S: Right. So I mean, absolutely there's, there's key lifestyle factors, right? Like even in the word supplement, it means supplemental, right? It is. It is to be added on top of other things. It is not to fundamentally
Julie Michelson: So you don't like take the Big Mac and then take this analytic and eat the Big Mac. You don't take a Big Mac, I guess you eat it I would. It would be forced upon me, but, so it's . It's not something that's gonna make up for an unhealthy lifestyle necessarily
James S: No, I mean, to certain extent, the right supplementation can offset damage that you're doing from bad lifestyle habits. And it's not the goal, right? The goal is invest in yourself, invest in happiness, in health and vitality. Do the right lifestyle things, and [Page//00:32:00] then add the right kinds of supplementations and technologies on top of that for even better effect.
So yeah, I mean, I mean, across the board the most important things that people can generally do for health is good quality sleep, good diet, good exercise. And in this regard, it is very similar, right? Quality sleep is one of the things that's most readily gonna support the natural ability to clear out senescent cells.
Cause the, I mean, there's different ways it happens, but primarily it's an immune function, right? The immune system is designed to kill off senescent cells, but when it's overly taxed, it stops having the ability to do that as effectively as we know. Sleep has a massive impact on immune function. And then diet is key, and particularly in this area.
I mean there are certain types of foods, things that are high in polyphenols that are gonna be really good, but one of the keys here is actually intermittent fasting. Right. Having extended periods of time where you're not taking in calories is one of the things that's going to help [Page//00:33:00] trigger, well, both agy, but also the ability to clear up cellular in essence.
So from a lifestyle perspective, key things would be, yeah, eat, eat healthy foods high in polyphenols. So that largely means. Not overly processed and correct colorful things. And if you can and are willing to experiment with intermittent fasting and get your sleep dialed in
Julie Michelson: And I do look at this as such an up level as somebody who focuses on all of those things, not only in my life, but in the life of my clients. The intermittent fasting really for me changed my life, and that's a whole nother podcast. But it was a key piece and, and so, and one of the. Reasons, I think fasting, whether it's, you know, a fast, fast or having some kind of intermittent fasting in your life it is for, you know, [Page//00:34:00] aji and, and I think that there's, where just experientially I see that direct relation to reducing inflammation is remarkable.
And so I look. Lytic is like, Oh my gosh, you know, here's an up level. And the beauty is scientifically, even if you ha if you've not, you don't practice intermittent fasting. I mean, this, again, it's not an either or. Ideally it's an and, but you're still gonna get benefit. It's not like you have to take it and fast.
You're we're just talking about, you know, ways to be supporting the body. Ideal.
James S: Yeah, I mean that, that's sort of an ideal, It's not something that most people realistically are gonna do. Cause you know, like for those who aren't familiar, right? Intermittent fasting. Yeah, I mean there's a bunch of different versions, but the kind of common popular version is you don't eat for 16 hours and then you eat within an eight hour window of the day, because [Page//00:35:00] at 16 hours is when this process called aji kicks in, which if you're not familiar, aji is the word actually translates to selfe.
But essentially it's where the body. Digests particular pieces of cells that are no longer healthy and functioning and processes them out to improve overall health and self function. And there there's a close tie between SEN and a toy actually. Like most of the ingredients that are in our lytic product have also quite a bit of evidence to support and increase theology.
So though that wasn't the primary focus of this particular product, it is one of the, the likely secondary benefits. But yeah, intermittent fasting is essentially you try to keep your eating within an eight hour window. So let's say from noon to 8:00 PM. And then outside of that, you try to not have an e caloric intake.
Now black coffee is usually still okay within that cuz there's not really calories and there's actually some compounds in there that [Page//00:36:00] support all of these processes. But generally it's, you know, water during the rest of the time and then you keep your meals within that window and it has tremendous benefits.
And if you're willing and able to do that, awesome. If not, that's cool too. Just try to make relatively good food choices and. The Big Mac is usually not one of those,
Julie Michelson: No and I don't even, It's not even food. Let's be real. No, and, and I have to throw in my, you know, and you did say it, but I'm gonna highlight. That, that eating window isn't, is not ideal for everybody. And it certainly doesn't mean that if you've never played with intermittent fasting, you should immediately, you know, just go for that eight hour window.
But you, you find, and it may change. I mean, there was a period where I felt best when ate one. That was just, it just naturally that's how we evolved. And it, and it changes, so it'll listen to your body [Page//00:37:00] as well as you do it. You may have already answered this. I, I always love to give listeners because gen generally, there's a lot of, you could do this, you could do that really.
Information and nuggets. But then I put you on the spot and ask you for that. One step listeners can take today, and it certainly could be one of the things you already said to, to start to really move the needle and improve their health.
James S: It's always so hard to narrow down. Right.
Julie Michelson: I have to pick one.
James S: So it's interesting. If I was gonna give one, it actually wouldn't be any of the three main things I mentioned. Right? I said the keys are sleep. Diet, exercise, but to me, those are all tools in the direction of what is most important, which is pursue that which makes you feel most alive. Right, And that can look like a million different things for somebody. For one person, it's singing, right? For another person it's dancing. For another person, it's quality [Page//00:38:00] time with friends for one, for somebody else. It is, you know, spending time in the kitchen and really devoting yourself to making healthy food and, and being present to it.
And it, and honestly doesn't matter what it is. Whatever it is that moves you, that makes you light up, that makes you. Delighted. That makes you want to get out of bed in the morning, do more of that.
Julie Michelson: I love that I, I.
James S: side of approach to how to not just be healthy, but how to live a great life. And it's the thing that as a society, we suck at.
Right. We get so focused on all the things we have to do,
Julie Michelson: back burner that all the time.
James S: right? I mean, we've all had.
Julie Michelson: your motivator to then do all the other things is. When you're pursuing the, I, this is not the word you use, but joy, like we, we, that's what drives us, which goes back to the colia, right? This feeling the most like you and it is so different.[Page//00:39:00]
James S: Well, and the beautiful thing with that is if you do that, you have way more energy and resources for everything else,
Julie Michelson: it's fuel.
James S: And it doesn't matter what makes you feel live if you move in that direction. You have a better outlook on life. You have a, they're almost inherently going to make better choices. You're gonna choose to spend less time in relationships and dynamics that are stressful and painful. You're either gonna get out of them or you're gonna take better dietary choices. Like it doesn't, It's gonna cross over into every other part of life.
Julie Michelson: the trickle down effect. Yeah. Amazing. Oh my gosh. So amazing where everything's gonna be in the notes, but for those that just listen on the go, where's the best place to find you? They're like, I need to hear more from him.
James S: I mean, best [Page//00:40:00] places go to neural hacker.com. Right. They're, you're, I mean, I have content on there, but I mean, we have a whole team of just amazing physicians, PhDs that are putting out all kinds of great content. Obviously, you know, products are there. But you know, we, we focus very heavily on research and product, but also on education.
And so, you know, there's a lot of resources there to dive into and not just in the domain of health right. Like that is our core focus. But a lot of our content research is also oriented around sort of how to support the more healthy functioning civiliz. Cuz it ties into why we started the business, right?
The, that initial goal I talked about of, you know, how do you make people more intelligent, more competent, and more empathetic. That empathy part was how do you drive better decision making in the world as a whole? So we also try to expose people to some of the things that would help create more understanding of what does the world need at scale.
And then as you become healthier, as you [Page//00:41:00] become, More capable. You get to devote more resources to your own life and your own happiness. But as we all know, contribution is one of the key things that makes life phenomenal. And so we try to support and encourage things in that direction.
Julie Michelson: And you guys do an amazing job. It is part of, it's not just the products that make your company stand out and, and make that contribution so big. So everybody, you know, go to neurohacker.com and, and check it out. And, and I don't ever, I don't push, I only promote what I know and what I, what I. Really see, make a difference for people.
So I would say, you know, check out the products as well because they, they are amazing. They're the best you're gonna find, for sure.
James S: Thank you.
Julie Michelson: James, thank you so much. You've shared amazing gold with us today.
James S: Thanks for having me. This was great. I, I really enjoyed it. Glad to get to share.
Julie Michelson: For everyone listening, remember, you get [Page//00:42:00] the show notes and transcripts by visiting inspired living.show. I hope you had an amazing time and enjoyed this episode as much as I did. I'll see you next week.
James brings his lifelong focus on using [Page//00:01:00] business and innovation to affect large scale change for the benefit of humanity. Today's conversation focuses on senescent cells or zombie cells, and how using SY Alytics may be the anti-aging key you are looking for.
James, welcome to the podcast.
James S: Thank you. It's a delight to be here,
Julie Michelson: I would love for you to share a little bit of your story with people before I hit record. I was kind of, well, to me you're a celebrity . But, but I, I want people to really kind of just get an idea of how you got to be making the contribution you are and, and what, you know, what brought you to this world.
James S: Yeah, yeah. No, absolutely. And it's funny cause you know, there's of course so many different parts to the story, right? But guess I'll just say like the holistic medicine has been kind of a life passion for me from very, very young My, my mom has a disease called interstitial cystitis, and she had [Page//00:02:00] done, she had participated in a drug trial when I was like five years old, and it nearly killed her.
And she ended up in the hospital for I think, like three months. And, you know, was very close to death, even if she was gonna recover, was never supposed to walk again. And like she. Pro ice skater, you know, prior to this. And so, I mean, obviously huge contrast. And when she was in the hospital somebody had given her a book on Iveta medicine and she had nothing else to do, so she devoured the book, ended up finding solutions and, you know, kind of eventually left the hospital and went down this natural health track.
Got. You know, dramatically better and a year later was competing in ice shows again. And so like that was a kind of key turning point for I think me and my whole family, where it was like, okay, medicine in this traditional form has incredible applications and. It deeply lacks in some key areas. And taking a more cutting [Page//00:03:00] edge, more alternative kind of approach can oftentimes do as much, if not more than a path you can.
So that, I mean, really set a tone for the rest of life. But I think, you know, as, as it pertains kind of like to why, why narrow hacker, right? Why do we start Poly? That story really was. When, So when I was 18, I was in school at a vocational college studying alternative medicine and psychology. And right around the time I was graduating, the owner of the school, the founder of the school had said he wanted to semiretired.
Cause I wanted to teach, but he didn't want to run the business anymore. So in my 18 year old hub, I was like, Oh, I can do this. So I went out and raised money, which God knows why anyone gave me money at that age. And I bought the. And it was phenomenal. I was like incredibly passionate about the work.
It was definitely what I wanted to be doing with my life, but I had no skills. Like I didn't even know how to balance a checkbook. So here I am all of a sudden [Page//00:04:00] like 18 year old kid doesn't know didly and now I'm running a school. And so I made up for the lack of skill with just pure work. And, you know, 20, 22 hour days, take a short nap at my desk. What's that?
Julie Michelson: the American Dream.
James S: Exactly. I think we might need to update that dream.
Julie Michelson: Yeah. There is a better way. Heads neuro, hacker,
James S: it, it, it definitely took me some years to learn it, but I, I do not recommend pushing that hard, even at that age where you're almost bionic. But
Julie Michelson: or think you are. Yeah.
James S: Yeah, at least think you are. But yeah, so you know, I, after about three years of just ridiculous workload at 21, I had severe burnout. And I was like, I started having massive brain fog.
My memory stopped working. I started going into depression, which I was doing this work that I was deeply passionate about, and I was depressed. So then I started having an existential breakdown, like [Page//00:05:00] couldn't make sense of life. So I went on my healing journey. And you know, being in the field, I was fortunate to get exposed to a bunch of things and try all kinds of stuff.
But there was one therapy particularly that. Changed my world. And it, it was, I ended up going down to Mexico and doing this sort of experimental intravenous therapy that at the time I had no idea what it was. Later on, I realized it was high dose in ad and a combination of a bunch of acids. But I did three days of this drip for like nine hours a day, and it changed everyth.
And not in like a subtle way. Right. And f I mean, I went in depressed, unable to think, unable to retain thoughts and coming out I. Not only had all of my cognitive function back, but I was experiencing a sense of clarity that I had never experienced before. I had a sense of like capacity and motivation that was unlike anything that I had [Page//00:06:00] ever felt.
And then the thing that was super remarkable for me was my sense of empathy shot through the roof. And it, it became the situational where it was like I couldn't think about what I wanted to do in the world and not immediately be aware of the implications of that on the rest of the world and the people around me.
And so as I was sitting there, I was like, Holy shit, what would happen if this became available at scale? Right? If we could build something that would allow, you know, hundreds of thousands, millions of people to become drastically more intelligent, more confident, more capable, but also more empathetic. So, They had an intrinsic motive to use that competency and that intelligence, not only for personal gain, but for the greater good.
Like, ah,
Julie Michelson: World changing.
James S: so this was, this was the concept, right? And initially I actually tried to partner with the doctor who created that IV therapy. We were gonna open clinics. Unfortunately, like three weeks into that project, he became super ill and passed away and his research went away with, [Page//00:07:00] So here I was with this beautiful vision and no path.
And so then I spent several years while, you know, running other businesses, new other things, interviewing all the top neuroscientists, neurobiologists, chemists, formulators, and everyone was like, Yeah, this is a great concept. It's not doable. And and I just couldn't let it go. Right.
Julie Michelson: Thank you , for not letting it go.
James S: Yeah, so it was, it took me a long time, but eventually I ended up convincing my brother to partner with me and I had tried for years and he kept saying no. But he's, you know, a lot of people have probably seen him on podcasts. But he's one of the rare geniuses of the world and his background is in complex system science.
And I knew that if we could apply complex system science to the study of physiology, we could do things that the world had sort of never seen before in terms of healing and health optimization. And so eventually he agreed to partner. We dove into this like [Page//00:08:00] two year full on r and d process, both sort of developing.
Scientific model based on complex system science but also developing the first product, which was quality, right? Our broad spectrum cognitive enhancement. And that was essentially the, the birth of Neurohacker was A, you know, lofty vision, some semblance of tenacity that eventually panned out and, and seen amount of research.
And, you know, luckily it's, it's been a pretty extraordinary ride and process and, you know, given the opportunity to help a lot of people and hopefully more to come.
Julie Michelson: Which is, is incredible. I was telling you before we started, I have been a, a long time fan of the company, an early adopter, if you will. And I, I love. I always say my, my start in biohacking that led me to, to functional medicine, you know, the, the two worlds are, they really are, to me, [Page//00:09:00] ideal. Is it, It's both, right?
The best functional medicine docs are pulling from biohacking, and if you're biohacking properly, you're utilizing functional medicine. And so there's a synergy there. And so I love when I first found Colia the mind. I did, other than my group of biohacker. Like I didn't know anybody else taking it.
I did, you know, nobody else had heard of it. And, and so I love, now you know, how the company has grown. And I, you have, I I would love to do an interview for each of the products. I did share, you know, I am a, I am, not only do I love the contribution that the company is making by. Truly creating these products, you know, with not even just the, the science you pull together.
But. Your process of getting stuff to market and, and testing and, and you do have a group of us that are well, we're willing to, [Page//00:10:00] to be Guinea pigs and try, there's a trust level there so that you guys can tweak and continue to improve your products which is amazing. We're gonna jump, So I say anybody who's like, you know, what is this Neuro Hucker collective and what is Pia?
Look it up. I just learned. From a presentation this past weekend, I, I never even thought about it, like, what is the definition of Lia? And I was like, Oh, this makes so much sense. If somebody wants to know, well, like, how does a neutropic and a sleep enhancer and a lytic all tie together? Like, how is this one company?
But if you go back to colia, this, which is the experiential quality, Of what is like to be you. It's like. This is it, right? Like it's best mind, but you know, this is so, so thank you, thank you, thank you from the bottom of my heart for what you guys are doing and how you're doing it. And I [Page//00:11:00] want to jump into, This, you know, your newest product which I really do.
I, I, for me, obviously your first product changed my life because I still, When did that come out? I don't even know how many, how long I've been taking it.
James S: Quality of mind was our first one, and that came out in late 2016.
Julie Michelson: Okay. That makes sense.
James S: Entry into the world. Yeah, it's been a little bit now.
Julie Michelson: Yeah. And, and so, you know, that's a commitment. So I've, I've been, you know, using that ever, ever since then. But I, I real so that, you know, I know each, each product has the ability to change your life. You know, if I, and I always say, you know, it all comes down to if we're sleeping better, that quality of sleep, getting your mind to work.
But I'm really. Because of the, more of the, even the functional medicine piece. Excited about your latest and greatest. So [Page//00:12:00] let's talk a little bit about SCE essence and SY Analytics and what this is. Why are we even talking about it on an, an autoimmunity targeted podcast? You know, why does, you know?
Cause you're, you don't make products for three people. You know, it, it's really something that can enhance everybody's.
James S: Yeah, absolutely. I mean, it's interesting cause right, this whole area of cellular in essence like is so new people, I mean, most people that are listening right now have probably never even heard
Julie Michelson: That they won't even know. So let's even, let's start right there. What is sin Essence?
James S: Yeah. Yeah. So basically, Healthy cells are supposed to be able to continue to divide and reproduce, right? And then once they get to a point where they no longer have the ability to continue to divide and reproduce, then they're supposed to die off. Right? That's a process called apoptosis and. That's how the body sort of operates healthy.
But [Page//00:13:00] what ends up happening as we age and as we have more stressors and poor nutrition and, you know, various different things, is that oftentimes cells will become what's known as senescent or like commonly it's referred to as zombie cells, right? And what, mm-hmm.
Julie Michelson: me is like the perfect. For people to understand when you say zombie cells,
James S: Yeah, I mean, it makes perfect sense when you actually get to understand how it works, right? So basically a cell will get to a place where it's no longer able to divide and reproduce, but it doesn't die off. And so it's sort of alive, but it's not really doing anything. It no longer is able to do much in the way of energy output.
It doesn't have a lot of the beneficial. Traits that a cell normally does. So it's just sort of pseudo living, taking up resources. But part of why it's also called a zombie cell is it's not, It's not just the problem of it taking up resources and not providing benefit. It's also that it AITs certain proteins that turn the other cells [Page//00:14:00] around them into esent cells.
So in the same way that a zombie will try to eat your brains and it turns you into a zombie, right? These esent cells emit these chemicals, which then turn other ones into it, and that whole process drastically speeds up the aging process. And so this is essentially what you know, cellular esce is, and in the term sen lytic, which we'll be talking about a little bit, are the compounds that are researched for being able to kill off esent cells, right?
Being able to allow them to actually finish their life cycle and die off and make space for new healthy cells to be able to reproduce.
Julie Michelson: Which I, and I, I, again, I love the like, simple, I'm not a scientist . And so
James S: I'm not either. I just play one on
Julie Michelson: Yeah, when I, when I, and I'm, I know, I'm saying, I always say that I'm not a doctor and I don't play one on tv, . But if you, if you think of, you know, it's a cleanup, right? Like this is what we're talking about. And, and I like that you, you know, To, to take the zombie [Page//00:15:00] thing all the way that it's not joke, cuz I always kind of thought of it.
And so I learned a lot at the quality of presentation, the, this last weekend because I always thought of it kind of as just the first piece, right? I know we, you know, we get these esent cells and we, we want them gone, but they're not dying off. They're taking resources. I think of it. You know, I have a lot of house plants and I love to garden and, and so the pruning right?
We wanna get rid of those dead and dying leaves so that the, the rest of the plant is, is getting the good stuff. But then when you understand this kind of it thing, I think of it as like building a cellular army. We don't want, we don't want more and more of ourselves just hanging out, you know, grabbing buddies.
And I, I, I want to just for the audience's sake cuz some people may think like, anti, I'm not interested in anti-aging. Like, I just wanna feel well, I say this all the time to me the things [Page//00:16:00] we think of, the negative pieces of what we think of as aging is all, in my opinion, my humble just said, I'm not a scientist or a doctor
But it's all inflammation. That's why we, you know, my favorite word is inflammaging. And I, I wish I could figure out who actually coined it, cuz I can't, like, I've never been able to find out who the first person was to say that in public. And to me, autoimmunity is just further down the spectrum on that expression of inflammation.
And so by focusing anything we can do, To reduce inflammation to, you know, help reverse the aging process or add some grace to it is also the same things we need to be doing to improve our autoimmune symptoms and, and live fuller lives.
James S: I mean, this is sort of the beauty of the, the domain of like anti-aging research, right? Which this scene alytics fall squarely within that is, it's not just about. It's not [Page//00:17:00] anti-aging exclusively in the ways that people typically think about that, which is either how do you live longer or how do you look better for longer, right?
Like, these are both key things. And of course they're, they're good goals to pursue.
Julie Michelson: in a, in a way, but there's the piece of, I, my, the thing that fell outta my mouth on a podcast that I was like, Oh, I'm writing that down, is I, I wanna live young until I die. Like I, honestly, it's not about used to be about how long I live, cuz I didn't think I'd live to see 50. Now that I'm 53 and I feel younger than I did at 34, like, I just wanna live like this until I'm done.
Like, that's the, That's what we're talking about is that quality of life.
James S: Yeah, I mean, people get so focused on lifespan, right? How many years you're on the planet, and that's awesome. But like what we tend to focus more on is what we refer to as health span, right? How many years are you on the planet and thriving in health? Because even if we can develop [Page//00:18:00] technologies that allow for you to add, you know, 5, 10, 20 years to your life, but those last years are bedridden in pain, that's not actually a goal that most people are that attracted to.
Julie Michelson: No. Nor should
James S: we.
Julie Michelson: be
James S: Add and ears that are thriving health or, you know, don't even worry about adding ears. Just improve the quality of life during the time that you're here. And the beauty of so much of the stuff in the anti-aging space is like a lot of that work is being done at the cellular level. Right. That's one of the key things here in cellular senescence, right?
So when you're improving health at the cellular level, you're essentially going to improve everything because it is like the fundamental building block. And so, yes, there's of course things you wanna focus on depending on what your needs and conditions are to address specific. Symptoms to address specific parts of the body.
But when you can improve cellular health overall, there's just this net net benefit across everything. You feel [Page//00:19:00] better, you have more energy, more clarity of thinking. You heal faster. Like virtually
Julie Michelson: become a better human, which is, goes back to your story of, and know you're empathetic. You're, it's a, it becomes about, And not just survival. And, and so, you know, that's why we're having this conversation today. I'm, I'm excited about. So let's talk a little bit about SY Analytics and, and, and talk about how this is different, Right?
I, I just said I've been using your first product since I found it, which I believe was right away in 2016. Definitely by 2017, but I, I think it might have been 2016. I take that on a regular basis. And so let's kind of talk about this cycle of. You know, guide us through the, this amazing kind of cutting edge being involved in the anti-aging world.
You know, there are, this is, it's [Page//00:20:00] new, but it's not new, right? Like this, this idea. And there are prescriptions that have been used. There are what's new is that you're, this is accessible and, and effective and so, People can take charge. I'm all about giving, giving, creating power, right? Empowering people.
So let's talk about the, the actual product and. Kind of the, not the, the, the science behind it because we don't have enough time. And I don't know if I have the, well, I do have the brain power. I took my mind this morning. But you know what, it's because it is, it's a very, it's very different. And I think that the way you guys help us understand the, like, okay, why we're taking it and then how it works.
Is it, it that just makes sense.
James S: Yeah. So I mean, I guess like if we dive in, there's So cellular in essence, is one of what's known as the hallmarks of aging, right? There's, there's nine hallmarks of aging, and these are like the key areas that [Page//00:21:00] cause the aging process. And there's extensive research going into all of them. Some, you know, the world understands better than others.
Some we have more tools to be able to affect than others. But things like, so like cellular essence is one of them. Mitochondrial function is one of them. Stem cell exhaustion is one of them. Telomere length, right? So there, there's all these different hallmarks. There's like, for Neurohacker, there's two primary ones that we've dod deeply into so far, which is cellular, senescence, and mitochondrial function, right?
So we have another product called Quality of Life, which is this just phenomenal mitochondrial function product helps to improve. Cellular energy output, cellular metabolism dramatically boosts an ad levels like all kinds of cool stuff. As we move into cellulars essence, part of what makes this domain so exciting is it's ridiculously new.
And so like this is one of the first times in history where there's something available to actually have an impact here. So, Like the field of Esce has been [Page//00:22:00] researched for several decades now. Like we've known that these esent cells exist and we've known that they cause problems. But that was kind of the extent of what the research community understood, and there was never this understanding of, well, anything can be done about it.
And that was some really breakthrough research that only happened in 2015. Right. So this is super recent.
Julie Michelson: yeah.
James S: It was predominantly from Mayo Clinic and from scripts where they began using actually it was a drug trial with a drug called the stib, which is cancer drug. But what they found was that when they were giving patients the stib and then biopsying the tissues, they were starting to see dramatically less.
Esent cells. And then there started to be some other research where they were using dasatinib and corin to supplement that a lot of people probably have some familiarity with. And then you saw, you know, an even greater decrease. And so it's, it's only in the last, what is it, seven years, that there was any awareness that something could be done [Page//00:23:00] and.
Dasatinib definitely shows really promising results in this area, but it's also a pretty harsh drug that has serious consequences, and so that's where, you know, then the next stage of research started to began of, well, what else could mimic some of these effects? And do it with creating all the benefit, but without creating harm.
Right. And so then there started to be some studies with a number of other compounds, but particularly the two most research, most known are Cetin and Corin. And these are both, you know, somewhat commonly available supplements. And you know, all coming from plant extracts that show drastic decreases in the amount of esent cells in the body.
And then where the research has continued to evolve, and this is, you know, where we've been able to do some really, really interesting things is. So there's different, there's esent cells in all of the different types of tissue in the body, [Page//00:24:00] and this is something that a lot of the research community isn't actually even paying attention to yet.
But you have esent cells in, you know, skin tissue and in muscle tissue, and different compounds end up being able to kill off cells in different kinds of tissues more effectively. So, You know, there's, there's really not that much on the market right now. Around r are usually only one or two ingredients, and so they're effective, but they're predominantly killing esent cells in particular tissue types and not necessarily addressing whole body. And this is, as you know, like our approach is this whole systems's approach, right?
We're always looking to not just affect one or two narrow things, but how do we do this whole system upgrade? So we did this deep dive into research and found all of the compounds that had really meaningful backing for being able to address cells and all the different tissues and then put them all together, , right?
And
Julie Michelson: What a concept[Page//00:25:00]
James S: Yeah, and I mean, and I understand why a lot of companies don't do it, cuz I mean, it does take dramatically more hours of research. And you know, as you start using more ingredients, it's more expensive to produce. It's. More complicated to actually run through machinery. There's, there's lots of challenges, but for us, the goal has always been how do we make the very best thing that can exist and we'll figure out how to address the difficulties in getting there.
And so it's just become this phenomenal, phenomenal product where people are showing tremendous benefit in really short periods of time. Like kind of remarkably simple.
Julie Michelson: Which is amazing and
James S: I.
Julie Michelson: Oh, we had a little,
James S: Yeah, I mean we, you know, this product's only been, I think three. Are we, Do we
Julie Michelson: No, we're good. We're good. We're back. [Page//00:26:00] So the product just is new.
James S: you know. Yeah, so the etic product is quite new. It's only been out three months or so. So we're still continuing to do all kinds of follow up studies, but we did one study initially that was really compelling where, so one of the key areas where CYS and Cells will show up, that people will notice is joint health.
Right. As you start to have this build up of, of these unhealthy ENT cells, it tends to create things like, Joints, stiffness, pain, lack of mobility. So we, we did a study on that specifically, and what we found was over the course of people doing this product three cycles we found a 53% decrease in joint discomfort.
And a 51% decrease in difficulty doing regular tasks. And that's dramatic, right? Like cuz I mean, this was a very short period of time. We're talking under three months. And you know, [Page//00:27:00] for a lot of the people that were involved in the study, like the challenges they had were fairly significant. And all of a sudden now there's half of that.
Julie Michelson: Which is amazing. This was a group in their seventies? Yes.
James S: It, it ranged. Like with all of our studies, we, we generally try to get a pretty healthy range of both, you know, age, gender, everything. But yes, in this one we did air a little bit on the older side cuz that's where people
Julie Michelson: get your symptoms.
James S: noticeable effects.
Julie Michelson: Yeah. And that's something I wanna, I, I'm always, I'm very big on, you know, markers and tests where you can, and, and you, you mentioned it when you're talking about the earlier, you know how the studying Right now to truly see, you know, what's going on with the cells, you're talking biopsies is, nobody's gonna be going in.
Oh, I'm trying this new supplement and I'm gonna go in and get biopsied every three to six months to see what it's doing. But the remarkable thing is, as you mentioned already, you know, just the improvement and in quality of [Page//00:28:00] life and hitting so it is, is noticeable for, for people. You mentioned cycles, and I, I think this is so important to talk about this.
This is something that I think a lot of people aren't used to as far as how, how you use the product effectively,
James S: That a few minutes ago when you talked about pruning, right? So with most supplements, people are used to the idea that you take them all the time, right? You take 'em every day or you take 'em a few days a week. But when it comes to addressing esent cells, the research actually shows that the best way to address them is what's often referred to as the hit and run approach, right?
You do a large amount of this lytic compound. For a very short period of time, and then you take a break and then you do it again. Right? So the lytic product we developed is, it's essentially like a cellular cleanse. You do it two days on and then wait a month and then do it again. And [Page//00:29:00] it, it's very much like that pruning process, right?
Like if you had. Plant that had some yellow or dying leaves. If you were to actually go and prune it every single day for just a little tiny bit, it would actually take up way more resources from the plant and be counterproductive versus allowing a little bit of time to pass for more yellowing. And then you go and you prune those leaves.
And so it's that exact same process when you're talking about clearing out esent cells. And I think this is one of the reasons people have also liked the product. Actually, as you and I were talking about before the interview started, so many people struggle with consistency, right? You wanna take supplements, you know they're going to have benefit, but you know, do you build them into your lifestyle and remember to actually do it every day?
And so one of the cool things with this analytic is you don't actually have to, right? You take it two days and then you're off for a month and then you take it again. And that's sort of like, that's the recommended approach. Some people will wait longer. It obviously depends. You know [Page//00:30:00] how much cellular, in essence you think you have built up, how important it is to work on it.
You can do two days and then wait three months, but the sort of ideal is this sort of like monthly cellular detox.
Julie Michelson: Yeah. Which is also, you know, that's the coach in me is like, that works on the calendar. You know, my, my dogs get an, an injection. I give them a supplement for their joints once a month, you know, so, The beginning of the month, I'm already thinking like, Oh, this will go . You know, this will be my beginning to pay your mortgage and , take your lytic.
Which I love. One question that comes up a lot. I know because I got to listen to the questions in the, in the presentation last week is about, you know, additional behaviors or lifestyle adjustments of like, really is this gonna work if I'm just. Taking the supplements, Is there other things people should be doing to improve results or, you know, have in mind of [Page//00:31:00] like, okay, if, if we're now aware, like we really want this cellular clean out and optimization, what else should we be doing?
James S: Right. So I mean, absolutely there's, there's key lifestyle factors, right? Like even in the word supplement, it means supplemental, right? It is. It is to be added on top of other things. It is not to fundamentally
Julie Michelson: So you don't like take the Big Mac and then take this analytic and eat the Big Mac. You don't take a Big Mac, I guess you eat it I would. It would be forced upon me, but, so it's . It's not something that's gonna make up for an unhealthy lifestyle necessarily
James S: No, I mean, to certain extent, the right supplementation can offset damage that you're doing from bad lifestyle habits. And it's not the goal, right? The goal is invest in yourself, invest in happiness, in health and vitality. Do the right lifestyle things, and [Page//00:32:00] then add the right kinds of supplementations and technologies on top of that for even better effect.
So yeah, I mean, I mean, across the board the most important things that people can generally do for health is good quality sleep, good diet, good exercise. And in this regard, it is very similar, right? Quality sleep is one of the things that's most readily gonna support the natural ability to clear out senescent cells.
Cause the, I mean, there's different ways it happens, but primarily it's an immune function, right? The immune system is designed to kill off senescent cells, but when it's overly taxed, it stops having the ability to do that as effectively as we know. Sleep has a massive impact on immune function. And then diet is key, and particularly in this area.
I mean there are certain types of foods, things that are high in polyphenols that are gonna be really good, but one of the keys here is actually intermittent fasting. Right. Having extended periods of time where you're not taking in calories is one of the things that's going to help [Page//00:33:00] trigger, well, both agy, but also the ability to clear up cellular in essence.
So from a lifestyle perspective, key things would be, yeah, eat, eat healthy foods high in polyphenols. So that largely means. Not overly processed and correct colorful things. And if you can and are willing to experiment with intermittent fasting and get your sleep dialed in
Julie Michelson: And I do look at this as such an up level as somebody who focuses on all of those things, not only in my life, but in the life of my clients. The intermittent fasting really for me changed my life, and that's a whole nother podcast. But it was a key piece and, and so, and one of the. Reasons, I think fasting, whether it's, you know, a fast, fast or having some kind of intermittent fasting in your life it is for, you know, [Page//00:34:00] aji and, and I think that there's, where just experientially I see that direct relation to reducing inflammation is remarkable.
And so I look. Lytic is like, Oh my gosh, you know, here's an up level. And the beauty is scientifically, even if you ha if you've not, you don't practice intermittent fasting. I mean, this, again, it's not an either or. Ideally it's an and, but you're still gonna get benefit. It's not like you have to take it and fast.
You're we're just talking about, you know, ways to be supporting the body. Ideal.
James S: Yeah, I mean that, that's sort of an ideal, It's not something that most people realistically are gonna do. Cause you know, like for those who aren't familiar, right? Intermittent fasting. Yeah, I mean there's a bunch of different versions, but the kind of common popular version is you don't eat for 16 hours and then you eat within an eight hour window of the day, because [Page//00:35:00] at 16 hours is when this process called aji kicks in, which if you're not familiar, aji is the word actually translates to selfe.
But essentially it's where the body. Digests particular pieces of cells that are no longer healthy and functioning and processes them out to improve overall health and self function. And there there's a close tie between SEN and a toy actually. Like most of the ingredients that are in our lytic product have also quite a bit of evidence to support and increase theology.
So though that wasn't the primary focus of this particular product, it is one of the, the likely secondary benefits. But yeah, intermittent fasting is essentially you try to keep your eating within an eight hour window. So let's say from noon to 8:00 PM. And then outside of that, you try to not have an e caloric intake.
Now black coffee is usually still okay within that cuz there's not really calories and there's actually some compounds in there that [Page//00:36:00] support all of these processes. But generally it's, you know, water during the rest of the time and then you keep your meals within that window and it has tremendous benefits.
And if you're willing and able to do that, awesome. If not, that's cool too. Just try to make relatively good food choices and. The Big Mac is usually not one of those,
Julie Michelson: No and I don't even, It's not even food. Let's be real. No, and, and I have to throw in my, you know, and you did say it, but I'm gonna highlight. That, that eating window isn't, is not ideal for everybody. And it certainly doesn't mean that if you've never played with intermittent fasting, you should immediately, you know, just go for that eight hour window.
But you, you find, and it may change. I mean, there was a period where I felt best when ate one. That was just, it just naturally that's how we evolved. And it, and it changes, so it'll listen to your body [Page//00:37:00] as well as you do it. You may have already answered this. I, I always love to give listeners because gen generally, there's a lot of, you could do this, you could do that really.
Information and nuggets. But then I put you on the spot and ask you for that. One step listeners can take today, and it certainly could be one of the things you already said to, to start to really move the needle and improve their health.
James S: It's always so hard to narrow down. Right.
Julie Michelson: I have to pick one.
James S: So it's interesting. If I was gonna give one, it actually wouldn't be any of the three main things I mentioned. Right? I said the keys are sleep. Diet, exercise, but to me, those are all tools in the direction of what is most important, which is pursue that which makes you feel most alive. Right, And that can look like a million different things for somebody. For one person, it's singing, right? For another person it's dancing. For another person, it's quality [Page//00:38:00] time with friends for one, for somebody else. It is, you know, spending time in the kitchen and really devoting yourself to making healthy food and, and being present to it.
And it, and honestly doesn't matter what it is. Whatever it is that moves you, that makes you light up, that makes you. Delighted. That makes you want to get out of bed in the morning, do more of that.
Julie Michelson: I love that I, I.
James S: side of approach to how to not just be healthy, but how to live a great life. And it's the thing that as a society, we suck at.
Right. We get so focused on all the things we have to do,
Julie Michelson: back burner that all the time.
James S: right? I mean, we've all had.
Julie Michelson: your motivator to then do all the other things is. When you're pursuing the, I, this is not the word you use, but joy, like we, we, that's what drives us, which goes back to the colia, right? This feeling the most like you and it is so different.[Page//00:39:00]
James S: Well, and the beautiful thing with that is if you do that, you have way more energy and resources for everything else,
Julie Michelson: it's fuel.
James S: And it doesn't matter what makes you feel live if you move in that direction. You have a better outlook on life. You have a, they're almost inherently going to make better choices. You're gonna choose to spend less time in relationships and dynamics that are stressful and painful. You're either gonna get out of them or you're gonna take better dietary choices. Like it doesn't, It's gonna cross over into every other part of life.
Julie Michelson: the trickle down effect. Yeah. Amazing. Oh my gosh. So amazing where everything's gonna be in the notes, but for those that just listen on the go, where's the best place to find you? They're like, I need to hear more from him.
James S: I mean, best [Page//00:40:00] places go to neural hacker.com. Right. They're, you're, I mean, I have content on there, but I mean, we have a whole team of just amazing physicians, PhDs that are putting out all kinds of great content. Obviously, you know, products are there. But you know, we, we focus very heavily on research and product, but also on education.
And so, you know, there's a lot of resources there to dive into and not just in the domain of health right. Like that is our core focus. But a lot of our content research is also oriented around sort of how to support the more healthy functioning civiliz. Cuz it ties into why we started the business, right?
The, that initial goal I talked about of, you know, how do you make people more intelligent, more competent, and more empathetic. That empathy part was how do you drive better decision making in the world as a whole? So we also try to expose people to some of the things that would help create more understanding of what does the world need at scale.
And then as you become healthier, as you [Page//00:41:00] become, More capable. You get to devote more resources to your own life and your own happiness. But as we all know, contribution is one of the key things that makes life phenomenal. And so we try to support and encourage things in that direction.
Julie Michelson: And you guys do an amazing job. It is part of, it's not just the products that make your company stand out and, and make that contribution so big. So everybody, you know, go to neurohacker.com and, and check it out. And, and I don't ever, I don't push, I only promote what I know and what I, what I. Really see, make a difference for people.
So I would say, you know, check out the products as well because they, they are amazing. They're the best you're gonna find, for sure.
James S: Thank you.
Julie Michelson: James, thank you so much. You've shared amazing gold with us today.
James S: Thanks for having me. This was great. I, I really enjoyed it. Glad to get to share.
Julie Michelson: For everyone listening, remember, you get [Page//00:42:00] the show notes and transcripts by visiting inspired living.show. I hope you had an amazing time and enjoyed this episode as much as I did. I'll see you next week.
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James Schmachtenberger
James Schmachtenberger is a successful serial entrepreneur, with a lifelong focus on using business and innovation to effect large-scale change for the benefit of humanity. James is the co-founder and the CEO of Neurohacker Collective, a company focused on making groundbreaking products for health and well-being through complex systems science. His areas of expertise include nootropics, anti-aging and regenerative medicine, sleep and fast-paced entrepreneurialism.
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